engleski

Histological and histomorphometric analysis of pure b-tricalcium phosphate and biphasic b- tricalcium phosphate/hydroxyapatite used for maxillary sinus floor augmentation

Aim: The aim of the study was to perform a clinical sinus floor augmentation trial on the use of two different synthetic bone grafts and analyse their histological and histomorphometric characteristics. Material and Methods: Lateral maxillary sinus lift procedures were performed on a total of 60 patients. The patients were randomly and equally subdivided into two groups on the basis of the material used. One group of patients underwent lateral augmentations with pure b- three-calcium phosphate (b-TCP), whereas for the other group a two-phase combination of b- TCP and hydroxyapatite (60% HA and 40% b-TCP) was used. Six months following augmentation a trephine core was taken from the augmented region, and sent for histological and histomorphometric evaluation. Results: Histological analysis of both materials showed a regular osseous organization of the augmented area, with pronounced resorption in a pure b- TCP group. Foreign body reaction was not observed in both groups. A histomorphometric comparison of both materials indicated a slightly increased proportion of newly formed bone in the biphasic material group (38.4% vs. 36.1%). Biphasic material samples presented more residual material (32.6% vs. 30.2%) and less non- mineralized component (28.9% vs. 34.2%) when compared to pure b-TCP. However, these histomorphometric differences were found not to be statistically significant. Conclusion: Bone graft substitute materials used in this study are biocompatible and support bone regeneration at the osteoconductive level. A slight advantage has been found for the biphasic material with respect to the pure b-TCP regarding newly formed bone of the augmented sinus.

sinus floor augmentation ; b-three-calcium phosphate ; hydroxyapatite

Rad prezentiran kao "Poster Discussion"