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Pregled bibliografske jedinice broj: 765107

Diagnosis of Irritable Bowel Syndrome : Role of Potential Biomarkers

Plvašić, Ivana; Hauser, Goran; Tkalčić, Mladenka; Pletikosić, Sanda; Salkić, Nermin
Diagnosis of Irritable Bowel Syndrome : Role of Potential Biomarkers // Gastroenterology research and practice, (2015), 490183-1 doi:10.1155/2015/490183 (međunarodna recenzija, pregledni rad, znanstveni)

Diagnosis of Irritable Bowel Syndrome : Role of Potential Biomarkers

Plvašić, Ivana ; Hauser, Goran ; Tkalčić, Mladenka ; Pletikosić, Sanda ; Salkić, Nermin

Gastroenterology research and practice (1687-6121) (2015); 490183-1

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
Iritable Bowel Syndrome; Inflammation
(Irritable Bowel Syndrome; Inflammation)

Irritable bowel syndrome is a disorder diagnosed on symptom-based criteria without inclusion of any objective parameter measurable by known diagnostic methods. Heterogeneity of the disorder and overlapping with more serious organic diseases increase uncertainty for the physician’s work and increase the cost of confirming the diagnosis. This paper is an attempt to summarize the efforts to find adequate biomarkers for irritable bowel syndrome, which should shorten the time to diagnosis and reduce the cost. Most of the reviewed papers were observational studies from secondary care institutions. Since publication of the Rome III criteria in 2006, most recent studies use these for the recruitment of IBS patients. This is a positive step forward as future studies should use the same criteria, facilitating comparison of their results. Among the studied biomarkers, most evidence is provided for fecal calprotectin. Cutoff values for fecal calprotectin have still to be investigated prior to inclusion in the irritable bowel syndrome diagnostic algorithm.

Izvorni jezik

Znanstvena područja
Kliničke medicinske znanosti, Psihologija


Filozofski fakultet, Rijeka,
Medicinski fakultet, Rijeka,
Klinički bolnički centar Rijeka,
Sveučilište u Rijeci,
Fakultet zdravstvenih studija u Rijeci

Časopis indeksira:

  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus