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Novel 2-(substituted-phenyl)-6-amino-benzothiazole hydrochlorides : synthesis and antitumor activity


Karminski-Zamola, Grace; Racane, Livio; Stojković, Ranko; Tralić-Kulenović, Vesna; Pavelić, Krešimir
Novel 2-(substituted-phenyl)-6-amino-benzothiazole hydrochlorides : synthesis and antitumor activity // Abstracts of the XVIIth International Symposium on Medicinal Chemistry ; u: Drugs of the Future 27 (2002) (S) / Prous, J.R. (ur.).
Barcelona, 2002. str. 296-296 (poster, međunarodna recenzija, sažetak, znanstveni)


Naslov
Novel 2-(substituted-phenyl)-6-amino-benzothiazole hydrochlorides : synthesis and antitumor activity

Autori
Karminski-Zamola, Grace ; Racane, Livio ; Stojković, Ranko ; Tralić-Kulenović, Vesna ; Pavelić, Krešimir

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts of the XVIIth International Symposium on Medicinal Chemistry ; u: Drugs of the Future 27 (2002) (S) / Prous, J.R. - Barcelona, 2002, 296-296

Skup
International Symposium on Medicinal Chemistry (17 ; 2002)

Mjesto i datum
Barcelona, Španjolska, 01.-05.09.2002

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Benzothiazoles; antitumor activity

Sažetak
A series of hydrochloride or dihydrochloride salts of the novel 2-(4-substituted-phenyl)-6-amino-benzothiazoles antitumor agents, have been prepared in multistep synthesis starting from substituted benzaldehydes and 3-nitro-substituted o-amino-thiophenol and evaluated on their antitumor activity on following malignant human tumor cell lines : cervical carcinoma (HeLa), breast carcinoma (MCF-7), colon carcinoma (CaCO-2), laryngeal carcinoma (Hep-2), as well as on human fibroblast cell lines (WI-38):

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Ustanove
Institut "Ruđer Bošković", Zagreb,
Fakultet kemijskog inženjerstva i tehnologije, Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus