engleski

Homocystinuria, a Possible Explanation of the Akhenaten’s mystery

Pharaoh Amenophis IV (Amenhotep IV), also known as Akhenaten, is the most mysterious person in Egyptian history and he still remains the object of academic argues. This revolutionary king introduced a new concept in Egyptian religion and arts. It is still unexplained if images of him and his family were just an artistic outbreak from old Egyptian canon or an excellent paleopathological study. Several pathologic conditions were proposed to explain his appearance but neither is completely acceptable. We propose a different disease that he could have suffered of: homocystinuria – lack of cysthationine-β synthase. Our conclusion is that in comparison with up-to-date most convincing theory, that he was suffering of Marfan syndrome, our theory equally well explains his physical appearance but is better in explaining affecting and unaffecting of his relatives. However, the confirmation of both can be made only by DNA analysis. Still the method for DNA sampling is the subject of criticism.

Egypt; History of Medicine; Akhenaten; Ancient History; Pharaoh; Homocystinuria

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