engleski

The effect of age, anthropometric parameters, vertebral bone densitometry and ash density on iliac crest bone volume and microstructure

Background and Purpose: The purpose was to compare iliac crest bone static bone histomorphometry and vertebral bone densitometry as two methods frequently used in clinical practice. Patients and Methods: Cylindrical bone samples of the iliac crest bone (N=100) for bone histomorphometry and the whole bodies of the third lumbar vertebra (L3) (N=100) for bone densitometry and atomic absorption spectrometry were collected. Multiple regression analyses were carried out and results were considered significant when p<0.05 and 0.01. Results: Age was inversely proportional to all histomorphometric parameters except for Tb.Sp. Age predicted BV/TV with the largest share of contribution of 68%. Gender showed the highest share of contribution for the Tb.Th (32%), while BMD showed it for the Ct.Th (10%). Conclusions: After age and gender, BMD is the third strongest variable to predict iliac crest bone histomorphometric parameters, and thus we can conclude that iliac crest bone histomorphometry and vertebral bone densitometry are correlated, which is important for monitoring osteoporosis in good clinical practice

vertebral bone densitometry ; iliac crest bone volume ; microstructure

Naziv projekta: Uloga koštanog morfogenetskog proteina - 9 u akutnom i kroničnom oštećenju jetre (broj: 13.06.2.2.63.). Voditelj projekta: doc. dr. sc. Olga Cvijanović, dr. med.