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Pregled bibliografske jedinice broj: 763672

Pretransplantation hemodialysis strategy influences early graft function, surgical and infectious complications


Mikolašević, Ivana; Rački, Sanjin; Devčić, Bosiljka; Rački, Valentino; Prskalo, Mila; Orlić, Lidija
Pretransplantation hemodialysis strategy influences early graft function, surgical and infectious complications // Nephrology Dialysis Transplantation
London, United Kingdom: Oxford University Press, 2015. str. iii660-iii660 (poster, međunarodna recenzija, sažetak, znanstveni)


Naslov
Pretransplantation hemodialysis strategy influences early graft function, surgical and infectious complications

Autori
Mikolašević, Ivana ; Rački, Sanjin ; Devčić, Bosiljka ; Rački, Valentino ; Prskalo, Mila ; Orlić, Lidija

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Nephrology Dialysis Transplantation / - : Oxford University Press, 2015, Iii660-iii660

Skup
52nd ERA-EDTA Congress

Mjesto i datum
London, United Kingdom, 28-31.05.2015

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Extra haemodialysis session ; transplantation ; outcome

Sažetak
INTRODUCTION AND AIMS: Introduction and aim: There are only few data regarding the influence of an extra haemodialysis (HD) session immediately before the transplantation (tx) on the early-graft function. Furthermore, it is unclear whether ultrafiltration (UF) during pre-transplant HD should be avoided or not. The aim of this analysis was to investigate what is the influence of pre-transplant HD as well as HD with or without UF on the early-graft function, surgical and infectious complications in the patients receiving kidney transplant. METHODS: Methods: The study group comprised of 147 HD patients (mean age 58.1±11.8 years) receiving a cadaveric kidney graft in the Transplant Unit of the University Hospital Centre Rijeka between 2008 and 2014. In all patients HD was applied within 24-hours before the transplantation either routinely (the patient was scheduled in a regular treatment, 26.7%) or as an extra HD due to hyperkalaemia (58.9%) or fluid overload (14.4%). The primary analysis was performed in 147 patients. In this group, patients treated with HD (n=90) were compared to those who didn't received a HD treatment (n=57). In further analysis, 90 patients who received HD in the 24 h preceding tx were divided into two subgroups according to the UF application ; UF<500 ml (n=30) or UF≥500 ml (n=60). RESULTS: Results: There was no difference due to delay graft function (DGF), rejection crises, one-year graft and patient's survival between the patients that were treated with HD in comparison to those without HD treatment. The incidence of surgical complications (p=0.05) and infections (0.03) was significantly higher in the patients treated with HD during the first month after transplantation. Patients that were treated with UF≥500 ml had significantly higher incidence of DGF (p=0.05), higher values of serum creatinine at day 5 (p=0.03), 15 (p=0.04) and day 30 (p=0.05) after transplantation, higher incidence of surgical complications (p=0.02) and longer hospital stay (36.1±15.1 vs. 29±13.7 days ; p=0.03) in comparison to patients treated with UF<500 ml. There were no significant differences in the one-year graft survival between the patients treated with UF≥500 ml in comparison to the patients treated with UF<500 ml. CONCLUSIONS: Conclusion: Additional HD session before the tx is associated with higher incidence of surgical and infectious complications. Ultrafiltration during pre-tx dialysis is associated with more DGF, more surgical complications and longer hospital stay.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove
Medicinski fakultet, Rijeka,
Klinički bolnički centar Rijeka