engleski

Role of adipokinetic hormones in stress elicited by insecticides: Tribolium castaneum model

Adipokinetic hormones (AKHs) are insect neuropeptides which major function is to stimulate immune response and to maintain homeostatis in living organism. AKHs are primary induced in metabolism control, but they also activate insect's antioxidative system. In the present study, Tribolium castaneum (red flour beetle) was used as a model species, and two insecticides as stressors (pirimiphos- methyl and deltamethrin). Insects were exposed to insecticides alone and to insecticides in combination with AKH. Mortality, metabolism rate, and activity of oxidative stress biomarkers were measured after the treatment. AKH-deficient beetles were prepared using RNAi technology in order to investigate role of AKHs under stress conditions. They were exposed to the same conditions as normal beetle strain.

Tribolium castaneum ; insecticides ; adipokinetic hormones ; RNAi technology ; oxidative stress ; mortality

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