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Pharmacoeconomical and added value of acute heart failure studies

TITLE: Pharmacoeconomical and added value of acute heart failure studies OBJECTIVES: The aim of this study is to investigate the rationalisation of treating patients (pts) with acute heart failure (AHF). It is expected that creation of electronic online registry of hospitalized pts with AHF provides valuable information, which can make improvement in the treatment methodology. METHODS: The investigation was conducted from January 2014 to January 2015. Data was collected for hospitalized pts at Department of Internal Medicine. Investigators that performed interviewees were medical doctors employed by Sisters of Charity University Hospital Center. For the purpose of this study a register of pts and data was created. Online database contains epidemiological data, clinical, laboratory and diagnostic parameters as well the consumption of drugs. It is accompanied by the data of length of treatment and the number of repeated hospitalizations. Register is coded and pts data protected. Study was approved by local Ethics committee. Written informed consent was obtained from each pt according to Good Clinical Practice and Helsinki Declaration principles. RESULTS: Results of this study showed that the hospitalised pts have heaviest clinical presentation, and are often re- hospitalised. Pts frequently return with nearly the same symptoms, signs and comorbidities, with numerous co- morbidities and polypragmasia. Performed interviewees showed that they had poor knowledge of the reason for hospitalization, severity and type of disease. Despite the very poor initial knowledge there was great interest in the clarification of origin of disease symptoms and further therapy. By this study additional check- ups, monitoring of pts and their education was performed. CONCLUSION: The results of this study showed the added health value of conducting clinical studies consider performed additional check- ups, the quality of monitoring patients and their education. Availability of electronic base and use of analytical systems it is important to use pharmacoeconomic analysis in the treatment of pts with AHF. It is necessary to have data registers of the pts with AHF at the local and national levels for pharmacoeconomic analysis and the decisions on the regulation of the health care system. Continuing education is essential both for physicians and pts. Investment in education such as educational materials, making online applications and websites could contribute to reducing number of pts and current treatment burden on the health system. This might reduce the frequent re-hospitalizations and the length of hospitalization. Registries of pts with AHF provide valuable information and can be used in further pharmacoeconomic studies.

Research ; Acute heart failure ; Pharmacoeconimical value

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