New Amidino-benzimidazolyl Thiophenes ; Synthesis and Photochemical Synthesis (CROSBI ID 93894)
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Starčević, Kristina ; Boykin, W. David ; Karminski-Zamola, Grace
engleski
New Amidino-benzimidazolyl Thiophenes ; Synthesis and Photochemical Synthesis
New amidino-benzimidazolyl-substituted bis-1, 2-(2-thienyl)ethenes (4, 5, 6) and benzo[1, 2-b:4, 3-b]dithiophenes (8, 9 and 10) were prepared by the condensation of amidino-substituted o-phenylene diamines with corresponding dialdehydes (3 and 7). All prepared amidino-benzimidazolyl substituted compounds, are of particular interest, because they could serve as intercalators or groove binders on DNA in anticancer therapy.
amidines; benzimidazoles; thiophenes; photochemistry; antitumor agents
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