Napredna pretraga

Pregled bibliografske jedinice broj: 759289

THE IMPACT OF HEPATITIS C VIRAL INFECTION ON RENAL GRAFT AND PATIENT’S SURVIVAL – A SINGLE CENTER EXPERIENCE


Anić, Kata; Mikolašević, Ivana; Orlić, Lidija; Devčić, Bosiljka; Jakopčić, Ivan; Rački, Sanjin
THE IMPACT OF HEPATITIS C VIRAL INFECTION ON RENAL GRAFT AND PATIENT’S SURVIVAL – A SINGLE CENTER EXPERIENCE // Knjiga sažetaka ; 4th Congress of Nephrology of Bosnia and Herzegovina with international participation / Enisa Mesić (ur.).
Sarajevo, BIH, 2015. str. 90-90 (predavanje, međunarodna recenzija, sažetak, znanstveni)


Naslov
THE IMPACT OF HEPATITIS C VIRAL INFECTION ON RENAL GRAFT AND PATIENT’S SURVIVAL – A SINGLE CENTER EXPERIENCE

Autori
Anić, Kata ; Mikolašević, Ivana ; Orlić, Lidija ; Devčić, Bosiljka ; Jakopčić, Ivan ; Rački, Sanjin

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Knjiga sažetaka ; 4th Congress of Nephrology of Bosnia and Herzegovina with international participation / Enisa Mesić - , 2015, 90-90

Skup
4th Congress of Nephrology of Bosnia and Herzegovina with international participation

Mjesto i datum
Sarajevo, BIH, 22.-25.travnja, 2015

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Hepatitis C; transplantacija
(Hepatitis C; transplantation)

Sažetak
INTRODUCTION: It remains controversial whether hepatitis C infection (HCV) alters log-term patients and renal graft survival. Our aim was to analyze the effects of HCV infection on patients and graft survival. METHODS: We retrospectively examined the 23-year (1990-2013) data of 471 renal transplant recipients (RTRs) mean age 50.2±14 years who were anti-HCV negative and 21 RTRs mean age 49±8 years who were anti-HCV positive at the time of transplantation. We compared graft and patients survival rates and causes of death and graft failure in HCV-positive and HCV-negative RTRs. RESULTS: There was no statistically significant difference between the two groups related to age or gender and due to the duration of dialysis treatment before the transplantation The mean posttransplant follow-up of 471 HCV negative RTRs was 61.1±59.3 months and for 21 HCV positive RTRs was 75.3±44.3 months (p=NS).There was no significant difference due to acute rejection crisis during the first-year of follow up (p=NS). The mean values of serum creatinine didn’t showed any significant differences after one-year, two-years and five-years of follow-up between the HCV negative RTRs and HCV positive RTRs (p=NS). In the HCV positive RTRs the main reason for graft loss was a chronic allograft nephropathy (CAN) (42.9%) and acute rejection crisis (42.9%). On the other hand, CAN was the cause of graft loss in the 44.1% of HCV negative RTRs, while acute rejection was the cause of graft loss in the 22% of RTRs that were anti-HCV negative. There were no significant differences in the patients survival between the HCV positive RTRs and HCV negative groups of our renal transplant recipients (38.1% vs. 22.9% ; p=NS). CONCLUSION: According to our experience, patients and graft survival were not affected by HCV infection. Anti-HCV positively should not preclude chronic renal failure patients from renal transplantation.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove
Medicinski fakultet, Rijeka,
Klinički bolnički centar Osijek,
Klinički bolnički centar Rijeka