Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 75610

Possible role of bacterial and viral infections in miscarriages


Matovina, Mihaela; Husnjak, Koraljka; Milutin, Nina; Ciglar, Srećko; Grce, Magdalena
Possible role of bacterial and viral infections in miscarriages // Fertility and Sterility, 81 (2004), 3; 662-669 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 75610 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Possible role of bacterial and viral infections in miscarriages

Autori
Matovina, Mihaela ; Husnjak, Koraljka ; Milutin, Nina ; Ciglar, Srećko ; Grce, Magdalena

Izvornik
Fertility and Sterility (0015-0282) 81 (2004), 3; 662-669

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
miscarriage; karyotyping; placenta; PCR; bacterial infections; viral infections

Sažetak
To determine the role of infections in miscarriages. Chorionic villi from aborted material were subjected to cytogenetic evaluation and analyzed for the presence of Chlamydia trachomatis, Ureaplasma urealyticum, Mycoplasma hominis, human cytomegalovirus (HCMV), adeno-associated virus (AAV), and human papillomaviruses (HPV). Retrospective study. University hospital and academic research institution. Karyotyping and detection of bacterial and viral DNA by means of polymerase chain reaction (PCR) in placenta specimens. In 54 (50%) of 108 samples the karyotype was normal, in 38 (35%) samples it was abnormal, and in 16 (15%) samples karyotype was undetermined. No U. urealyticum, M. hominis, HCMV, or AAV-2 DNA was detected, while C. trachomatis DNA was detected in one (1%) and HPV DNA in eight (7%) samples. No significant correlation of HPV-positive findings with karyotype status was established. Our findings do not support a role of C. trachomatis, U. urealyticum, M. hominis, HCMV, or AAV infections in miscarriages during the first trimester of pregnancy. However, further investigation should be made to determine a possible involvement of HPVs in the development of genetic abnormalities of the fetus and in miscarriages.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
0044008
0098104
0101023

Ustanove
Klinička bolnica "Merkur",
Institut "Ruđer Bošković", Zagreb,
Hrvatska akademija znanosti i umjetnosti

Citiraj ovu publikaciju

Matovina, Mihaela; Husnjak, Koraljka; Milutin, Nina; Ciglar, Srećko; Grce, Magdalena
Possible role of bacterial and viral infections in miscarriages // Fertility and Sterility, 81 (2004), 3; 662-669 (međunarodna recenzija, članak, znanstveni)
Matovina, M., Husnjak, K., Milutin, N., Ciglar, S. & Grce, M. (2004) Possible role of bacterial and viral infections in miscarriages. Fertility and Sterility, 81 (3), 662-669.
@article{article, year = {2004}, pages = {662-669}, keywords = {miscarriage, karyotyping, placenta, PCR, bacterial infections, viral infections}, journal = {Fertility and Sterility}, volume = {81}, number = {3}, issn = {0015-0282}, title = {Possible role of bacterial and viral infections in miscarriages}, keyword = {miscarriage, karyotyping, placenta, PCR, bacterial infections, viral infections} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE