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Pregled bibliografske jedinice broj: 752332

Lung diffusion capacity in children with respiratory symptoms and untreated GERD


Mirić, Mirjana; Turkalj, Mirjana; Nogalo, Boro; Erceg, Damir; Perica, Marija; Plavec, Davor
Lung diffusion capacity in children with respiratory symptoms and untreated GERD // Medical science monitor, 20 (2014), 774-781 doi:10.12659/MSM.890336 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 752332 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Lung diffusion capacity in children with respiratory symptoms and untreated GERD

Autori
Mirić, Mirjana ; Turkalj, Mirjana ; Nogalo, Boro ; Erceg, Damir ; Perica, Marija ; Plavec, Davor

Izvornik
Medical science monitor (1234-1010) 20 (2014); 774-781

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Lang; children; GERD

Sažetak
BACKGROUND: Gastroesophageal reflux disease (GERD) is associated with many respiratory disorders, among which, chronic cough, laryngitis, and asthma are among the most common. We investigated lung function, including gas diffusion capacity, in children with poor asthma control or chronic laryngitis with untreated GERD. MATERIAL AND METHODS: A total of 71 children, aged 6-17 years, with chronic respiratory and other symptoms suggestive for GERD, were enrolled and divided into 2 groups: chronic laryngitis and asthma. Participants underwent 24-hour pH monitoring and lung function assessment, measurement of single- breath diffusing capacity of the lung for carbon monoxide (DLCO), and fraction of exhaled nitric oxide (FENO) measurement. RESULTS: 24-hour pH monitoring was positive for GERD in 92.1% of preselected children with asthma and 90.1% of children with chronic recurrent laryngitis. All flows (PEF, MEF75, MEF50, and MEF25) were significantly lower in the asthma group, while FENO and DLCO were significantly lower in the laryngitis group. A significant inverse relationship was found between DLCO and all reflux indexes in the laryngitis group. Each unit change of Johnson- DeMeester score and Boix- Ochoa score increased the odds for significantly lower DLCO in laryngitis patients by 3.9% and 5.5%, respectively. CONCLUSIONS: In children with uncontrolled asthma and chronic laryngitis, the regurgitation of gastric contents due to GERD contributes to poor asthma control and aggravation of chronic laryngitis. Despite having normal lung function, the gas diffusion capacity should be controlled in patients with GERD and chronic laryngitis, and it might be the very first abnormality in distal airways.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekti:
277-0000000-3436 - Usporedba učinaka dva načina vođenja terapije astme u djece 12-18 godina (Plavec, Davor, MZOS ) ( POIROT)
277-2770968-0963 - Rani pokazatelji razvoja alergijskih bolesti u djece (Turkalj, Mirjana, MZOS ) ( POIROT)

Ustanove:
Klinički bolnički centar Zagreb,
Dječja bolnica Srebrnjak

Profili:

Avatar Url Davor Plavec (autor)

Avatar Url Mirjana Mirić (autor)

Avatar Url Mirjana Turkalj (autor)

Avatar Url Damir Erceg (autor)

Avatar Url Boro Nogalo (autor)

Poveznice na cjeloviti tekst rada:

doi www.medscimonit.com

Citiraj ovu publikaciju:

Mirić, Mirjana; Turkalj, Mirjana; Nogalo, Boro; Erceg, Damir; Perica, Marija; Plavec, Davor
Lung diffusion capacity in children with respiratory symptoms and untreated GERD // Medical science monitor, 20 (2014), 774-781 doi:10.12659/MSM.890336 (međunarodna recenzija, članak, znanstveni)
Mirić, M., Turkalj, M., Nogalo, B., Erceg, D., Perica, M. & Plavec, D. (2014) Lung diffusion capacity in children with respiratory symptoms and untreated GERD. Medical science monitor, 20, 774-781 doi:10.12659/MSM.890336.
@article{article, author = {Miri\'{c}, Mirjana and Turkalj, Mirjana and Nogalo, Boro and Erceg, Damir and Perica, Marija and Plavec, Davor}, year = {2014}, pages = {774-781}, DOI = {10.12659/MSM.890336}, keywords = {Lang, children, GERD}, journal = {Medical science monitor}, doi = {10.12659/MSM.890336}, volume = {20}, issn = {1234-1010}, title = {Lung diffusion capacity in children with respiratory symptoms and untreated GERD}, keyword = {Lang, children, GERD} }
@article{article, author = {Miri\'{c}, Mirjana and Turkalj, Mirjana and Nogalo, Boro and Erceg, Damir and Perica, Marija and Plavec, Davor}, year = {2014}, pages = {774-781}, DOI = {10.12659/MSM.890336}, keywords = {Lang, children, GERD}, journal = {Medical science monitor}, doi = {10.12659/MSM.890336}, volume = {20}, issn = {1234-1010}, title = {Lung diffusion capacity in children with respiratory symptoms and untreated GERD}, keyword = {Lang, children, GERD} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Citati:





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