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Synthesis and Conformational Study of Bioconjugates Derived from 1-Acetyl-1'-aminoferrocene and α-Amino Acids


Čakić Semenčić*, Mojca; Kovač, Veronika; Kodrin*, Ivan; Barišić, Lidija; Rapić, Vladimir
Synthesis and Conformational Study of Bioconjugates Derived from 1-Acetyl-1'-aminoferrocene and α-Amino Acids // European journal of inorganic chemistry, (2015), 112-123 doi:10.1002/ejic.201402837 (međunarodna recenzija, članak, znanstveni)


Naslov
Synthesis and Conformational Study of Bioconjugates Derived from 1-Acetyl-1'-aminoferrocene and α-Amino Acids

Autori
Čakić Semenčić*, Mojca ; Kovač, Veronika ; Kodrin*, Ivan ; Barišić, Lidija ; Rapić, Vladimir

Izvornik
European journal of inorganic chemistry (1434-1948) (2015); 112-123

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Conformation analysis; Density functional calculations; Bioinorganic chemistry; Peptidomimetics; Hydrogen bonds; Circular dichroism

Sažetak
1, 1'-Disubstituted ferrocene conjugates present useful and efficient bioorganometallic constraint design to reduce the conformational flexibility of small peptides. In this study we present the first systematic conformational analysis of nonsymmetric ferrocene peptidomimetics (Boc-AA-NH-Fn-COMe ; Boc = tert-butoxycarbonyl ; AA = Gly, L-Ala, L-Val ; Fn = 1, 1-ferrocenylene) and their monosubstituted analogues(Boc-AA-NH-Fc ; Fc = ferrocenyl ; AA = Gly, L-Ala, L-Val).

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekt / tema
058-1191344-3122 - Metalocenski biokonjugati, heterocikli i makromolekule (Veronika Kovač, )
HRZZ-IP-2013-11-7444 - Organske molekule u kondenziranoj fazi: međudjelovanja i modeliranje (Hrvoj Vančik, )

Ustanove
Prehrambeno-biotehnološki fakultet, Zagreb,
Prirodoslovno-matematički fakultet, Zagreb

Citiraj ovu publikaciju

Čakić Semenčić*, Mojca; Kovač, Veronika; Kodrin*, Ivan; Barišić, Lidija; Rapić, Vladimir
Synthesis and Conformational Study of Bioconjugates Derived from 1-Acetyl-1'-aminoferrocene and α-Amino Acids // European journal of inorganic chemistry, (2015), 112-123 doi:10.1002/ejic.201402837 (međunarodna recenzija, članak, znanstveni)
Čakić Semenčić*, M., Kovač, V., Kodrin*, I., Barišić, L. & Rapić, V. (2015) Synthesis and Conformational Study of Bioconjugates Derived from 1-Acetyl-1'-aminoferrocene and α-Amino Acids. European journal of inorganic chemistry,, 112-123 doi:10.1002/ejic.201402837.
@article{article, year = {2015}, pages = {112-123}, DOI = {10.1002/ejic.201402837}, keywords = {Conformation analysis, Density functional calculations, Bioinorganic chemistry, Peptidomimetics, Hydrogen bonds, Circular dichroism}, journal = {European journal of inorganic chemistry}, doi = {10.1002/ejic.201402837}, issn = {1434-1948}, title = {Synthesis and Conformational Study of Bioconjugates Derived from 1-Acetyl-1'-aminoferrocene and α-Amino Acids}, keyword = {Conformation analysis, Density functional calculations, Bioinorganic chemistry, Peptidomimetics, Hydrogen bonds, Circular dichroism} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


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