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Pregled bibliografske jedinice broj: 749719

Autoimmune encephalitis - therapeutic dilemmas


Šulentić, Vlatko; Hajnšek, Sanja; Nanković, Sibila; Petelin Gadže, Željka; Čajić, Ivana; Bujan Kovač, Andreja
Autoimmune encephalitis - therapeutic dilemmas // Neurologia Croatica / Hajnšek, Sanja ; Petravić, Damir ; Poljaković, Zdravka (ur.).
Zagreb: Denona d.o.o., 2014. str. 21-22 (predavanje, domaća recenzija, sažetak, stručni)


CROSBI ID: 749719 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Autoimmune encephalitis - therapeutic dilemmas

Autori
Šulentić, Vlatko ; Hajnšek, Sanja ; Nanković, Sibila ; Petelin Gadže, Željka ; Čajić, Ivana ; Bujan Kovač, Andreja

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Neurologia Croatica / Hajnšek, Sanja ; Petravić, Damir ; Poljaković, Zdravka - Zagreb : Denona d.o.o., 2014, 21-22

Skup
4. hrvatski kongres "Dileme u neurologiji" i 3. hrvatski kongres iz intenzivne neurologije s međunarodnim sudjelovanjem

Mjesto i datum
Rovinj, Hrvatska, 30.09.2014. - 05.10.2014

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Domaća recenzija

Ključne riječi
autoimmune encephalitis; epilepsy
(autoimmune envephalitis; epilepsy)

Sažetak
Autoimmune limbic encephalitis is a form of encephalitis characterized by specific antibodies to cell-surface antigens, specific clinical presentation and, in some cases, connection with different neoplasms. One of the main clinical characteristics are temporal lobe seizures. The fever-induced refractory epileptic encephalopathy syndrome (FIRES) and new onset refractory status epilepticus (NORSE) are very often characterized by development of super-refractory status epilepticus and fatal outcome. Although the etiology of the mentioned seizures is unknown, it is possible that it is connected with some form of autoimmune disorder, which should be confirmed by further investigations. Therapeutic guidelines recommend corticosteroids, immunotherapy and cyclophosphamide as the last therapeutic choice for both disorders, but there is still a question when to start to treat, what the first therapeutic line is, and also how aggressively to treat. Despite a number of published papers that describe individual experiences, there are still no clear therapeutic algorithms. In this paper, we present our experiences in the treatment of patients with autoimmune encephalitis. We think that therapy should be more aggressive and, sometimes, in the beginning of treatment, we suggest combined immunotherapy. In the cases of unsatisfactory results of treatment, we suggest quick switch to another kind of immunotherapy because the mentioned disorders have unfortunately a high rate of mortality and are associated with major disability. Sometimes the choice of therapy depends on the etiology of the mentioned diseases.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
108-1080315-0297 - Odrednice i rana dijagnoza bolesti motoričkih neurona u populaciji Hrvatske (Bilić, Ervina, MZOS ) ( CroRIS)

Ustanove:
Medicinski fakultet, Zagreb,
Klinički bolnički centar Zagreb


Citiraj ovu publikaciju:

Šulentić, Vlatko; Hajnšek, Sanja; Nanković, Sibila; Petelin Gadže, Željka; Čajić, Ivana; Bujan Kovač, Andreja
Autoimmune encephalitis - therapeutic dilemmas // Neurologia Croatica / Hajnšek, Sanja ; Petravić, Damir ; Poljaković, Zdravka (ur.).
Zagreb: Denona d.o.o., 2014. str. 21-22 (predavanje, domaća recenzija, sažetak, stručni)
Šulentić, V., Hajnšek, S., Nanković, S., Petelin Gadže, Ž., Čajić, I. & Bujan Kovač, A. (2014) Autoimmune encephalitis - therapeutic dilemmas. U: Hajnšek, S., Petravić, D. & Poljaković, Z. (ur.)Neurologia Croatica.
@article{article, author = {\v{S}ulenti\'{c}, Vlatko and Hajn\v{s}ek, Sanja and Nankovi\'{c}, Sibila and Petelin Gad\v{z}e, \v{Z}eljka and \v{C}aji\'{c}, Ivana and Bujan Kova\v{c}, Andreja}, year = {2014}, pages = {21-22}, keywords = {autoimmune encephalitis, epilepsy}, title = {Autoimmune encephalitis - therapeutic dilemmas}, keyword = {autoimmune encephalitis, epilepsy}, publisher = {Denona d.o.o.}, publisherplace = {Rovinj, Hrvatska} }
@article{article, author = {\v{S}ulenti\'{c}, Vlatko and Hajn\v{s}ek, Sanja and Nankovi\'{c}, Sibila and Petelin Gad\v{z}e, \v{Z}eljka and \v{C}aji\'{c}, Ivana and Bujan Kova\v{c}, Andreja}, year = {2014}, pages = {21-22}, keywords = {autoimmune envephalitis, epilepsy}, title = {Autoimmune encephalitis - therapeutic dilemmas}, keyword = {autoimmune envephalitis, epilepsy}, publisher = {Denona d.o.o.}, publisherplace = {Rovinj, Hrvatska} }




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