engleski

The encrustates on urological double J stent - physco-chemical analyses

In humans, one of the pathological forms of biomineralization in the body is a process in which the complex chemical systems, such as the urine, precipitated inorganic salts such as the kidney and / or urinary stones of different composition. This process is influenced by physico-chemical, genetic, endocrine, anatomic, climate, inflammatory and others factors. The disease is defined as urolithiasis and is still a serious health, social and sociological problem. Double J stent has been established as very valuable medical tool in treatment of numerous urological conditions. As such it has its advantages and drawbacks. The complications of double J stent are well documented and in the most cases are not life-treating. The most common “technical” complication is formation of stent encrustations which render stent nonfunctional. The stent encrustation is most easily prevented by stent replacement. The etiological factors of the stent encrustation, besides biofilm formation and inflammation, are not well documented. The aim of this research was to analyze selected etiological factors and their role in the stent encrustation. The secondary objective was to test the hypothesis that chemical composition of the encrustate must be same as of primary stone, with premise that alkali urine will favor the phosphate stones. Deposits on JJ stent removed from the urinary tract in selected groups of patients were characterized by thermal FT-IR spectroscopic analysis and gravimetric analysis (TG) . The composition of the encrustates on the urological stents were compared with the composition of urinary stoneand it is shown that they are not consistent. In conclusion it can be said that some of the parameters were not significantly different in patients with and without encrustates. The most common encrustate component is apatite, then struvite, and least common are calcium oxalate encrustates. The composition of the encrustates were not always identical at different levels.

J stent ; urology ; encrustates ; analysis

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