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Pregled bibliografske jedinice broj: 742483

Health-related quality of life among patients with postmenopausal osteoporosis treated with weekly and monthly bisphosphonates


Kaštelan, Darko; Vlak, Tonko; Lozo, Petar; Gradiser, Marina; Mijić, Šime; Nikolić, Tatjana; Miškić, Blaženka; Car, Dolores; Tajsić, Gordana; Dušek, Tina et al.
Health-related quality of life among patients with postmenopausal osteoporosis treated with weekly and monthly bisphosphonates // Endocrine research, 35 (2010), 4; 165-173 doi:10.3109/07435800.2010.505218 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 742483 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Health-related quality of life among patients with postmenopausal osteoporosis treated with weekly and monthly bisphosphonates

Autori
Kaštelan, Darko ; Vlak, Tonko ; Lozo, Petar ; Gradiser, Marina ; Mijić, Šime ; Nikolić, Tatjana ; Miškić, Blaženka ; Car, Dolores ; Tajsić, Gordana ; Dušek, Tina ; Jajić, Zrinka ; Grubišić, Frane ; Poljičanin, Tamara ; Bakula, Miro ; Džubur, Fedja ; Strizak-Ujević, Matilda ; Kadojić, Mira ; Radman, Maja ; Vugrinec, Mirela ; Kuster, Zrinka ; Pekez, Marijeta ; Radović, Endi ; Labar, Ljubica, Crnčević-Orlić, Željka ; Koršić, Mirko

Izvornik
Endocrine research (0743-5800) 35 (2010), 4; 165-173

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
bisphosphonates ; osteoporosis ; quality of life ; EQ-5D ; OPTQoL

Sažetak
The present study was designed to assess the effect of monthly ibandronate on health-related quality of life (HR-QoL) in patients with postmenopausal osteoporo- sis previously treated with weekly bisphosphonates. HR-QoL was assessed by Euroqol (EQ-5D) and Osteoporosis Targeted Quality of Life (OPTQoL) questionnaires. The EQ- 5D questionnaire showed significant improvement associated with ibandronate treatment, occurring in mobility (p < 0.01), usual activity (p < 0.01), pain/discomfort (p < 0.05), and anxiety/depression (p < 0.05). In addition, ibandronate treatment considerably improved patients’ perceived health on a visual analog scale (p < 0.001). For the OPTQoL questionnaire, patients reported less physical difficulty (p < 0.001), fewer adaptations in their lives (p < 0.001), and less fear (p < 0.001) with ibandronate than with weekly bisphosphonates. The study demonstrated that patients who were transferred from weekly bisphosphonates to a monthly ibandronate experienced improved HR-QoL.

Izvorni jezik
Engleski



POVEZANOST RADA


Projekti:
108-1080229-0142 - Molekularni mehanizmi učinaka imunosnih poremećaja na kost (Grčević, Danka, MZOS ) ( POIROT)
062-0620226-0208 - Kost kao ciljni organ u šećernoj bolesti i upalnim bolestima crijeva (Crnčević Orlić, Željka, MZOS ) ( POIROT)

Ustanove:
Medicinski fakultet, Rijeka,
Opća bolnica "Dr. Josip Benčević"

Citiraj ovu publikaciju

Kaštelan, Darko; Vlak, Tonko; Lozo, Petar; Gradiser, Marina; Mijić, Šime; Nikolić, Tatjana; Miškić, Blaženka; Car, Dolores; Tajsić, Gordana; Dušek, Tina et al.
Health-related quality of life among patients with postmenopausal osteoporosis treated with weekly and monthly bisphosphonates // Endocrine research, 35 (2010), 4; 165-173 doi:10.3109/07435800.2010.505218 (međunarodna recenzija, članak, znanstveni)
Kaštelan, D., Vlak, T., Lozo, P., Gradiser, M., Mijić, Š., Nikolić, T., Miškić, B., Car, D., Tajsić, G. & Dušek, T. (2010) Health-related quality of life among patients with postmenopausal osteoporosis treated with weekly and monthly bisphosphonates. Endocrine research, 35 (4), 165-173 doi:10.3109/07435800.2010.505218.
@article{article, year = {2010}, pages = {165-173}, DOI = {10.3109/07435800.2010.505218}, keywords = {bisphosphonates, osteoporosis, quality of life, EQ-5D, OPTQoL}, journal = {Endocrine research}, doi = {10.3109/07435800.2010.505218}, volume = {35}, number = {4}, issn = {0743-5800}, title = {Health-related quality of life among patients with postmenopausal osteoporosis treated with weekly and monthly bisphosphonates}, keyword = {bisphosphonates, osteoporosis, quality of life, EQ-5D, OPTQoL} }
@article{article, year = {2010}, pages = {165-173}, DOI = {10.3109/07435800.2010.505218}, keywords = {bisphosphonates, osteoporosis, quality of life, EQ-5D, OPTQoL}, journal = {Endocrine research}, doi = {10.3109/07435800.2010.505218}, volume = {35}, number = {4}, issn = {0743-5800}, title = {Health-related quality of life among patients with postmenopausal osteoporosis treated with weekly and monthly bisphosphonates}, keyword = {bisphosphonates, osteoporosis, quality of life, EQ-5D, OPTQoL} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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