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Pregled bibliografske jedinice broj: 740518

Molecular and cellular approach in the study of antioxidant/prooxidant properties of Micromeria croatica (Pers.) Schott


Šamec, Dunja; Gruz, Jiri; Durgo, Ksenija; Kremer, Dario; Kosalec, Ivan; Valek Žulj, Lidija; Martinez, Sanja; Salopek-Sondi, Branka; Piljac-Žegarac, Jasenka
Molecular and cellular approach in the study of antioxidant/prooxidant properties of Micromeria croatica (Pers.) Schott // Natural product research, 29 (2015), 18; 1770-1774 doi:10.1080/14786419.2014.999334 (međunarodna recenzija, članak, znanstveni)


Naslov
Molecular and cellular approach in the study of antioxidant/prooxidant properties of Micromeria croatica (Pers.) Schott

Autori
Šamec, Dunja ; Gruz, Jiri ; Durgo, Ksenija ; Kremer, Dario ; Kosalec, Ivan ; Valek Žulj, Lidija ; Martinez, Sanja ; Salopek-Sondi, Branka ; Piljac-Žegarac, Jasenka

Izvornik
Natural product research (1478-6419) 29 (2015), 18; 1770-1774

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Antioxidant ; cytotoxicity ; Micromeria croatica (Pers.) Schott. ; polyphenols ; prooxidant

Sažetak
Phytochemical composition and antioxidant activity of three wild populations of endemic Illyric-Balcanic species Micromeria croatica (Pers.) Schott have been evaluated with respect to plant organ and growing location. Multivariate analysis (PCA) was performed to visualize (dis-)similarity among samples and identify correlations between phytochemical variables that explain the most variability. The tested leaf extract from locality Bačić kuk exhibited protective effects against ROS- induced damage of DNA and inhibition of lipid peroxidation, while it caused oxidative degradation of protein in the BSA assay at higher concentrations. This extract also exhibited cytotoxic activity and facilitated the formation of ROS in the HEp2 cell line, in a dose-dependent manner.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija



POVEZANOST RADA


Projekt / tema
006-0000000-3178 - Mikromorfološka i kemotaksonomska istraživanja nekih vrsta porodice Lamiaceae (Dario Kremer, )
058-0582261-2246 - Utjecaj mutagena i antimutagena na molekularne procese u stanici (Reno Hrašćan, )
098-0982913-2829 - Molekularna regulacija biljnog razvitka (Branka Salopek-Sondi, )
125-0822161-2982 - INHIBICIJA KOROZIJE PRIRODNIM SPOJEVIMA: OD MOLEKULSKIH MODELA DO PRIMJENE (Sanja Martinez, )

Ustanove
Farmaceutsko-biokemijski fakultet, Zagreb,
Prehrambeno-biotehnološki fakultet, Zagreb,
Institut "Ruđer Bošković", Zagreb,
Fakultet kemijskog inženjerstva i tehnologije, Zagreb

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka:


  • CAB Abstracts
  • Cambridge Crystallographic Data Centre
  • Chemical Abstracts Service
  • National Library of Medicine
  • PubMed
  • Science Citation Index Expanded and Scopus


Citati