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Pregled bibliografske jedinice broj: 739750

Synthesis of ferrocene-labelled 2-aminopyrimidine derivatives via homogeneous catalytic carbonylation


Fehér, Csaba; Habuš, Ivan; Wouters, Johan; Skoda-Földes, Rita
Synthesis of ferrocene-labelled 2-aminopyrimidine derivatives via homogeneous catalytic carbonylation // Monatshefte für Chemie, 145 (2014), 12; 1981-1986 doi:10.1007/s00706-014-1299-1 (međunarodna recenzija, članak, znanstveni)


Naslov
Synthesis of ferrocene-labelled 2-aminopyrimidine derivatives via homogeneous catalytic carbonylation

Autori
Fehér, Csaba ; Habuš, Ivan ; Wouters, Johan ; Skoda-Földes, Rita

Izvornik
Monatshefte für Chemie (0026-9247) 145 (2014), 12; 1981-1986

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Metallocenes ; Heterocycles ; Homogeneous catalysis ; Crystal structure

Sažetak
The palladium-catalyzed carbonylation of iodoferrocene was investigated in the presence of 2-aminopyrimidine derivatives as nucleophiles. 2-Amino-4-hydroxy-6-methylpyrimidine was found to act both as an O- and an N-nucleophile, leading to an ester and an amide derivative, respectively. Together with other spectroscopic methods, the structure of both products was proved by X-ray crystallography. 2-(Ferrocenoylamino)-4-chloro-6-alkylpyrimidines were obtained during carbonylation of iodoferrocene and 2-amino-4-chloro-6-alkylpyrimidines. The formation of a dimeric product via two subsequent carbonylation steps was also observed. The products may have practical importance as electrochemically detectable biosensors or building blocks for supramolecular assemblies.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekt / tema
098-0982915-2948 - Amino-beta-laktami - intermedijari u sintezi biološki interesantnih spojeva (Vlasta Tomašić, )

Ustanove
Institut "Ruđer Bošković", Zagreb

Autor s matičnim brojem:
Ivan Habuš, (70961)

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI


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