engleski

Treatment of neuroendocrine tumors of the pancreas - our experience

Background. Neuroendocrine tumors are rare neoplasms of the pancreas. Aim of this research is to present the way of treating such tumors at our Institute. Methods. Retrospective analysis of patient histories treated at our institute. Results. Over a six-year period we have treated 13 patients (9 males and 4 females) with neuroendocrine tumors of the pancreas, mean age 42.69 years. Of the mentioned patients, 10 at the time of presentation had symptoms signaling towards possible pancreatic involvement, while 3 patients had nonspecific symptoms. Five tumors were found in the head and 8 in the body and tail of the pancreas. All patients were surgically treated, of which 3 underwent cephalic duodeno- pancreatectomy (according to Whipple), 6 distal splenopancreatectomy and in 4 cases other types of surgery were performed. Of the operated tumors, one had lymph node metastases, while 3 had liver metastases. One lethal outcome was recorded. In all other cases, recovery went well without signif- icant complications. Conclusions. According to our experience, although neuroendocrine tumors have a low prevalence in the general population, late appearance of symptoms and their non-specificity makes diagnosis and adequate patient care difficult. The surgical procedures involved are often complicated and very de- manding for seriously ill patients, but they remain the treatment of choice.

neuroendocrine tumors ; pancreas

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