engleski

Nutritional NaCl intake and bone remodeling in young healthy people

Sodium alters calcium metabolism by increasing excretion of calcium, and through this might influence bone metabolism. Purpose of this investigation was to asses if habitual intake of sodium has any effect on peak bone mass and indicators of bone metabolism. Habitual intake of sodium was assessed by questionnaire on sample of 41 young people that volunteered for study. To eliminate bias that could influence results, information on physical activity and nutritional intakes of important nutrients have been considered. Bone density and bone mineral content were measured by dual x-ray absorptiometry, and six biochemical markers were assessed from blood samples using ELISA: osteocalcin, C-terminal procollagen type I peptide, receptor activator kappa B ligand, pyridinoline, parathyroide hormone and osteoprotegerin. After adjustments for intake of calcium and vitamin D, there were no differences in bone mineral density and bone mineral content, or in concentration of any of biochemical markers between the groups formed according to sodium intake. These results bring us to conclusion that habitual sodium intake above recommended level is notdetrimental for bone remodeling in young healthy people.

nutrition ; sodium intake ; bone remodeling

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