engleski

Psychobiological model of personality and psychopharmacotherapy outcomes in treatment of depression and schizophrenia

In diagnising why some patients respond and other do not respond to treatments raised the clinically very important body of research consideeringwhether patients' personality characteristics might predict outcomes of pharmacotherapeutic treatment . Personality can be a predictor of a psychiatric disorder either owing to their common genetic background or because it enhances exposure of the subject to environmental risk factors. The results of the studies using psychobiological model are reviewed. The studies show that personality temperament dimension Harm Avoidance and character dimension Self-directedness predict coutcomes of the pharmacological treatment of depression, but the result for other psychiatric disorders are sparse.The studies are not straightforward in recommendations for ttreatment choice dependent of personality dimensions.

personality; psychosocial model; depression; schizophrenia; adherence; treatment-resistance

nije evidentirano