UNILATERAL ROSACEA APPEARING AT THE SITE OF CHRONIC RADIODERMATITIS (CROSBI ID 618690)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Čarija, Antoanela ; Vukšić, Ivan ; Puizina-Ivić, Neira ; Marasović, Dujomir
engleski
UNILATERAL ROSACEA APPEARING AT THE SITE OF CHRONIC RADIODERMATITIS
Rosacea is a condition that predominantly affects the convexities of the central aspect of the face. In our patient rosacea was predominantly on the left side at the site of chronic radiodermatitis. Rosacea is rarely unilateral. In one epidemiological study 14% of patients had unilateral lesions.1 Sezer and al described a 40-year-old man developing an erythematous rash on the right side of his face 3 weeks after a herpes zoster infection at the same location, a Wolf's isotopic response 2. In our case we could say it is also a case of a Wolf’s isotopic response. Research supports that an immune response of helper-inducer T-cell infiltrates occurs, surrounding the Demodex antigens in patients with rosacea. But is Demodex truly pathogenic? Conflicting evidence indicates that Demodex does not induce an inflammatory response in patients with rosacea. Moreover, Demodex is found in large numbers of healthy individuals without rosacea.5 Two histological studies indicated that inflammatory infiltrates a predominantly perivascular not perifollicular. 6, 7 Our patient has less pilosebaceous units because of the chronic radiodermatitis. That would suggest less Demodex mites, and still rosacea was more present at the site with less Demodex. It seems that in our patient, Demodex is not an important pathogenic factor.
rosacea; chronic radiodermatitis; unilateral
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Podaci o prilogu
2009.
objavljeno
Podaci o matičnoj publikaciji
Podaci o skupu
18th EADV Congress
poster
07.10.2009-11.10.2009
Berlin, Njemačka