Gastric lesion development in normal and pylorus ligated rats after cervical vagotomy (CROSBI ID 212594)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Ćorić, Valentina ; Čulig, Josip ; Zoričić, Ivan ; Sallmani, Ahmet ; Mikulandra, Simon ; Bogdan, Stjepan ; Šimičević, Velimir ; Bulić, Krešimir ; Kolega, Marko ; Derniković, Krešimir ; Đačić, Sanja ; Karakas, Ivan ; Seiwerth, Sven ; Grabarević, Željko ; Sikirić, Predrag ; Petek, Marijan ; Ručman, Rudolf ; Jelić, Ivan
engleski
Gastric lesion development in normal and pylorus ligated rats after cervical vagotomy
The main purpose of this study was to further investigate the effects of vagotomy on gastric lesion development. In contrast to the usual subdiaphragmal vagotomy, a different vagotomy at the level of the trigonum caroticum was used both alone and in combination with pylorus ligation (done immediately after vagal transection). The animals were killed 15 min. 30 min, 1 h and 6 f following vagotomy. No damaging effects of sham- vagatomy, or obvious negative effects of cervical vagotomy were noted. Prominent lesions appeared after 1 h in rats subjected to cervical vagotomy and significantly increased lesions in the early period of pylorus ligation were noted. No further aggravation in pylorus ligated rats (even an apparent amelioration at 1-h interval) and no lesions in rats with cervical vagotomy in the latter period could be explained in terms of a lack of reactivity due to exhaustion preceding fatal outcome. Consistent with this, the rats subjected to cervical vagotomy died shortly after the 6-h period.
gastric lesion ; pylorus ; cervical vagotomy ; pylorus ligation ; aggravation ; death
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Podaci o izdanju
87 (5)
1993.
335-337
objavljeno
0928-4257
1769-7115
10.1016/0928-4257(93)90040-Z
Povezanost rada
Kliničke medicinske znanosti, Temeljne medicinske znanosti