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Pregled bibliografske jedinice broj: 734523

Hair Iodine for Human Iodine Status Assessment


Momčilović, Berislav; Prejac, Juraj; Višnjević, Vjeran; Skalnaya, Margarita V.; Mimica, Ninoslav; Drmić, Stipe; Skalny, Anatoly V.
Hair Iodine for Human Iodine Status Assessment // Thyroid, 24 (2014), 6; 1018-1026 doi:10.1089/thy.2012.0499 (međunarodna recenzija, članak, znanstveni)


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Naslov
Hair Iodine for Human Iodine Status Assessment

Autori
Momčilović, Berislav ; Prejac, Juraj ; Višnjević, Vjeran ; Skalnaya, Margarita V. ; Mimica, Ninoslav ; Drmić, Stipe ; Skalny, Anatoly V.

Izvornik
Thyroid (1050-7256) 24 (2014), 6; 1018-1026

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Hair ; Human iodine deficiency ; Sex related
(hair ; human iodine deficiency ; sex related)

Sažetak
Today, human iodine deficiency is, after iron, the most common nutritional deficiency in de-veloped European and underdeveloped third world countries. A current biological indicator of iodine status is urinary iodine, which reflects very recent iodine exposure ; a long-term indicator of iodine status remains to be identified. We analyzed hair iodine in a prospective, observational, cross-sectional, and exploratory study involving 870 apparently healthy Croatians (270 men and 600 women). Hair iodine was analyzed with in-ductively coupled plasma mass spectrometry. The hair iodine median was 0.499 jug/g, and was 0.482 and 0.508 fig/g for men and women respec- tively, suggesting no sex-related difference. We studied hair iodine uptake by analyzing the logistic sigmoid saturation curve of the median derivatives to assess iodine deficiency, adequacy, and excess. We estimated overt iodine deficiency to occur when hair iodine concentration was below 0.1—0.15 jug/g. Then there was a saturation range interval of about 0.1-2.0 fig/g where the deposition of iodine in the hair was linearly increasing (R2 = 0.994). Eventually, the sigmoid curve became saturated at about 2.0 jug/g and upward, suggesting ex- cessive iodine exposure. Hair appears to be a valuable and robust biological indicator tissue for assessing long-term iodine status. We propose that an adequate iodine status corresponds with hair iodine uptake saturation of 0.565-0.739 fig/g (55-65%).

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
022-0222412-2405 - Metali - biokompatibilnost i stres u alopeciji, depresiji i dijabetesu (Berislav Momčilović, )
292-0222412-2405 - Metali - biokompatibilnost i stres u alopeciji, depresiji i dijabetesu (Berislav Momčilović, )

Ustanove
Medicinski fakultet, Zagreb,
Klinika za psihijatriju Vrapče,
Klinički bolnički centar Zagreb,
Institut za istraživanje i razvoj održivih eko sustava

Profili:

Avatar Url Ninoslav Mimica (autor)

Avatar Url Berislav Momčilović (autor)

Avatar Url Stipe Drmić (autor)

Citiraj ovu publikaciju

Momčilović, Berislav; Prejac, Juraj; Višnjević, Vjeran; Skalnaya, Margarita V.; Mimica, Ninoslav; Drmić, Stipe; Skalny, Anatoly V.
Hair Iodine for Human Iodine Status Assessment // Thyroid, 24 (2014), 6; 1018-1026 doi:10.1089/thy.2012.0499 (međunarodna recenzija, članak, znanstveni)
Momčilović, B., Prejac, J., Višnjević, V., Skalnaya, M., Mimica, N., Drmić, S. & Skalny, A. (2014) Hair Iodine for Human Iodine Status Assessment. Thyroid, 24 (6), 1018-1026 doi:10.1089/thy.2012.0499.
@article{article, year = {2014}, pages = {1018-1026}, DOI = {10.1089/thy.2012.0499}, keywords = {hair, human iodine deficiency, sex related}, journal = {Thyroid}, doi = {10.1089/thy.2012.0499}, volume = {24}, number = {6}, issn = {1050-7256}, title = {Hair Iodine for Human Iodine Status Assessment}, keyword = {hair, human iodine deficiency, sex related} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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