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Pregled bibliografske jedinice broj: 732116

Outbreak of nosocomial bacteremias, caused by Enterobacter gergoviae and Enterobacter aerogenes, in the neonatal intensive care unit, case - control study


Boban, Nataša; Jerončić, Ana; Punda-Polić, Volga
Outbreak of nosocomial bacteremias, caused by Enterobacter gergoviae and Enterobacter aerogenes, in the neonatal intensive care unit, case - control study // Signa Vitae, 6 (2011), 1; 27-32 (međunarodna recenzija, članak, znanstveni)


Naslov
Outbreak of nosocomial bacteremias, caused by Enterobacter gergoviae and Enterobacter aerogenes, in the neonatal intensive care unit, case - control study

Autori
Boban, Nataša ; Jerončić, Ana ; Punda-Polić, Volga

Izvornik
Signa Vitae (1334-5605) 6 (2011), 1; 27-32

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Neonatal intensive care unit; bacteremia; Enterobacter gergoviae; Enterobacter aerogenes; risk factors

Sažetak
In this case-control study we describe epidemiological characteristics and evaluate risk factors for bacteremias caused by a rare human pathogen Enterobacter gergoviae, and Enterobacter aerogenes, among neonates in the intensive care unit, under conditions of nosocomial outbreak. Crude rate of bacteremias was 16 per 1000 admissions. Bacteremias most commonly occurred between 7th to 30th day of hospitalization and were 1.9 times more frequent in males than females. The following risk factors were significantly associated with the development of bacteremias: a) colonization or infection of neonates prior to the onset of bacteremia with Enterobacter spp. (OR=3.4, 95%CI=1.2-9.9) or non-Enterobacter spp. (OR=7.9, 95%CI=1, 2-52.5) ; b) use of antimicrobial drugs most notably ceftazidime (OR = 7.8, 95% CI = 1.6.-38.6), or amikacin (OR = 7.5, 95% CI = 2.8-19.9) ; and c) invasive interventions: mechanical ventilation (OR = 4.7, 95% CI = 1.6-13.5), umbilical catheterization (OR = 3.1, 95% CI = 1.1-13.3), or nasogastric tube insertion (OR = 3.8, 95% CI = 1.8-8). These results show that some previously described risk factors for developing Enterobacter bacteremia were equally applicable in the case of Enterobacter gergoviae infections. In addition, the report represents an important contribution to establishing E. gergoviae as a relevant human pathogen with epidemiological potential, as it is the first case-control report in the region and one of a few in the world, analyzing outbreaks of bacteremias in the neonatal intensice care unit (ICU) caused by E. gergoviae.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
216-0481153-1148 - Patogeni koje prenose člankonošci u južnoj Hrvatskoj (Volga Punda-Polić, )

Ustanove
Medicinski fakultet, Split

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


Uključenost u ostale bibliografske baze podataka:


  • MEDLINE
  • SCOPUS