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Hybrid myxoinflammatory fibroblastic sarcoma/hemosiderotic fibrolipomatous tumor of the ankle following repeated trauma

Myxoinflammatory fibroblastic sarcoma and hemosiderotic fibrolipomatous tumor are rare, slow-growing soft tissue tumors of the distal extremities with recurrent potential. Recent cytogenetic studies have shown a t(1 ; 10)(p22 ; q24) or der(10)t(1 ; 10) in combination with aberrations of chromosome 3 in a limited number of cases of both entities. Here we report a case of a 42-year- old female with a soft tissue tumor of the ankle showing hybrid morphologic features of myxoinflammatory fibroblastic sarcoma and hemosiderotic fibrolipomatous tumor, a der(10)t(1 ; 10), and abnormalities of chromosome 3. This hybrid lesion provides further evidence for a close relationship between these 2 tumor types.

fibroblastic sarcoma

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