Evaluation of cationic microspheres with melatonin using eye-related bioavailability prediction models. (CROSBI ID 617574)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Duvnjak Romić, Marieta ; Juretić, Marina ; Cetina-Čižmek, Biserka ; Pepić, Ivan ; Hafner, Anita ; Lovrić, Jasmina ; Filipović-Grčić, Jelena
engleski
Evaluation of cationic microspheres with melatonin using eye-related bioavailability prediction models.
Developed cell-based epithelial cornea model is suitable for the prediction of eye-related bioavailability of drug delivered by chitosan- based systems. MCP were shown to interact with epithelial cornea barrier in safe and reversible manner. However, in case of melatonin, it resulted in no increase in permeability across cornea model suggesting transcellular melatonin transport.
corneal barrier; transport pathway; biointerface
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Podaci o prilogu
39-40.
2014.
objavljeno
Podaci o matičnoj publikaciji
Farmacevtski Vestnik
Žakelj, Simon ; Grabnar, Iztok ; Mrhar, Aleš
Ljubljana: Slovensko farmacevtsko društvo
Podaci o skupu
10th Central European Symposium on Pharmaceutical Technology
predavanje
18.09.2014-20.09.2014
Portorož, Slovenija
