engleski

Molecular changes of Wnt signaling play important roles in astrocytic tumor etiology

In the present study key players of wnt signaling, beta-catenin (CTNNB1), TCF1 and LEF1, adenomatous polyposis coli (APC) and axin (AXIN1) were investigated in the set of human astrocytic brain tumors. Our findings contribute to understanding of human astrocytic brain tumor genetic profile and suggest that molecular changes of wnt signaling play important roles in astrocytic tumor etiology.

wnt signaling pathway; astrocytic brain tumor

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