Napredna pretraga

Pregled bibliografske jedinice broj: 729001

Environmental occurrence, fate and transformation of benzodiazepines in water treatment


Kosjek, T.; Perko, S.; Zupanc, M.; Zanoški Hren, Marijana; Landeka Dragičević, Tibela; Žigon, D.; Kompare, B.; Heath, E.
Environmental occurrence, fate and transformation of benzodiazepines in water treatment // Water research, 46 (2012), 2; 355-368 doi:10.1016/j.watres.2011.10.056 (međunarodna recenzija, članak, znanstveni)


Naslov
Environmental occurrence, fate and transformation of benzodiazepines in water treatment

Autori
Kosjek, T. ; Perko, S. ; Zupanc, M. ; Zanoški Hren, Marijana ; Landeka Dragičević, Tibela ; Žigon, D. ; Kompare, B. ; Heath, E.

Izvornik
Water research (0043-1354) 46 (2012), 2; 355-368

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Diazepam; Oxazepam; Bromazepam; Environment; Treatment; Transformation

Sažetak
Benzodiazepine derivatives are prescribed in large quantities globally and are potentially new emerging environmental contaminants. Unfortunately, a dearth of data exists concerning occurrence, persistence and fate in the environment. This paper redresses this by reviewing existing literature, assessing the occurrence of selected benzodiazepine anxiolytics (diazepam, oxazepam and bromazepam) in wastewater influent and effluent and surface water from Slovenia, evaluating their removal during water treatment and identifying the transformation products formed during water treatment. Their occurrence was monitored in hospital effluent, river water and in wastewater treatment plant influent and effluent. The study reveals the presence of benzodiazepine derivatives in all samples with the highest amounts in hospital effluents: 111 ng L1, 158 ng L1 and 72 ng L1 for diazepam, bromazepam and oxazepam, respectively. Removal efficiencies with respect to biological treatment of diazepam were 16e18% (oxic), 18e32% (anoxic/oxic), 53e76% (oxic/anoxic) and 83% (oxic/anoxic/oxic/anoxic cascade bioreactors), while the removal oxazepam was 20e24% under anoxic conditions. Coupled biological and photochemical treatment followed by the adsorption to activated carbon resulted in a removal efficiency of 99.99%. Results reveal the recalcitrant nature of benzodiazepine derivatives and suggest that only combinational treatment is sufficient to remove them. In addition, eight novel diazepam and four novel oxazepam transformation products are reported.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija



POVEZANOST RADA


Ustanove
Prehrambeno-biotehnološki fakultet, Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Citati