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Pregled bibliografske jedinice broj: 727408

Levels of Selected Aqueous Humor Mediators (IL-10, IL-17, CCL2, VEGF, FasL) in Diabetic Cataract.


Mitrović, Sanja; Kelava, Tomislav; Šućur, Alan; Grčević, Danka
Levels of Selected Aqueous Humor Mediators (IL-10, IL-17, CCL2, VEGF, FasL) in Diabetic Cataract. // Ocular immunology and inflammation, 14 (2014), 2; 159-166 doi:10.3109/09273948.2014.949779 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 727408 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Levels of Selected Aqueous Humor Mediators (IL-10, IL-17, CCL2, VEGF, FasL) in Diabetic Cataract.

Autori
Mitrović, Sanja ; Kelava, Tomislav ; Šućur, Alan ; Grčević, Danka

Izvornik
Ocular immunology and inflammation (0927-3948) 14 (2014), 2; 159-166

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Aqueous humor; cataract; chemokines; cytokines; type 2 diabetes mellitus Read More: http://informahealthcare.com/doi/abs/10.3109/09273948.2014.949779

Sažetak
Purpose: To compare levels of selected mediators in serums and aqueous humor (AH) of type 2 diabetes mellitus cataract patients with senile cataract patients, and to determine their association with postoperative corneal edema (CE). Methods: Patients (32 senile and 29 diabetic cataract) undergoing standardized phacoemulsification combined with intraocular lens implantation were recruited. CE was assessed using an ordinal scale (grade 0 to 3). IL-10, CCL2, IL- 17, FasL, and VEGF were measured by ELISA. Results: Diabetic patients had higher AH levels of VEGF (p = .042) and IL-10 (p = .021), lower AH levels of FasL (p = .048), and higher serum levels of CCL2 (p = .002). AH levels of CCL2 were higher in diabetic patients with more severe CE at the first postoperative day (p = .012). Conclusions: We found disturbed AH microenvironment in diabetic cataract, with significant changes for VEGF, IL-10, and FasL. Higher CCL2 was associated with the development of early postoperative CE in diabetic patients.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekti:
108-1080229-0142 - Molekularni mehanizmi učinaka imunosnih poremećaja na kost (Grčević, Danka, MZOS ) ( POIROT)
108-1080229-0341 - B limfociti, makrofagi i podrijetlo osteoklasta (Katavić, Vedran, MZOS ) ( POIROT)
108-1080229-0140 - Molekularne interakcije koštanog i imunološkog sustava (Marušić, Ana, MZOS ) ( POIROT)

Ustanove:
Medicinski fakultet, Zagreb

Profili:

Avatar Url Danka Grčević (autor)

Avatar Url Sanja Mitrović (autor)

Avatar Url Alan Šućur (autor)

Avatar Url Tomislav Kelava (autor)

Citiraj ovu publikaciju

Mitrović, Sanja; Kelava, Tomislav; Šućur, Alan; Grčević, Danka
Levels of Selected Aqueous Humor Mediators (IL-10, IL-17, CCL2, VEGF, FasL) in Diabetic Cataract. // Ocular immunology and inflammation, 14 (2014), 2; 159-166 doi:10.3109/09273948.2014.949779 (međunarodna recenzija, članak, znanstveni)
Mitrović, S., Kelava, T., Šućur, A. & Grčević, D. (2014) Levels of Selected Aqueous Humor Mediators (IL-10, IL-17, CCL2, VEGF, FasL) in Diabetic Cataract.. Ocular immunology and inflammation, 14 (2), 159-166 doi:10.3109/09273948.2014.949779.
@article{article, year = {2014}, pages = {159-166}, DOI = {10.3109/09273948.2014.949779}, keywords = {Aqueous humor, cataract, chemokines, cytokines, type 2 diabetes mellitus Read More: http://informahealthcare.com/doi/abs/10.3109/09273948.2014.949779}, journal = {Ocular immunology and inflammation}, doi = {10.3109/09273948.2014.949779}, volume = {14}, number = {2}, issn = {0927-3948}, title = {Levels of Selected Aqueous Humor Mediators (IL-10, IL-17, CCL2, VEGF, FasL) in Diabetic Cataract.}, keyword = {Aqueous humor, cataract, chemokines, cytokines, type 2 diabetes mellitus Read More: http://informahealthcare.com/doi/abs/10.3109/09273948.2014.949779} }
@article{article, year = {2014}, pages = {159-166}, DOI = {10.3109/09273948.2014.949779}, keywords = {Aqueous humor, cataract, chemokines, cytokines, type 2 diabetes mellitus Read More: http://informahealthcare.com/doi/abs/10.3109/09273948.2014.949779}, journal = {Ocular immunology and inflammation}, doi = {10.3109/09273948.2014.949779}, volume = {14}, number = {2}, issn = {0927-3948}, title = {Levels of Selected Aqueous Humor Mediators (IL-10, IL-17, CCL2, VEGF, FasL) in Diabetic Cataract.}, keyword = {Aqueous humor, cataract, chemokines, cytokines, type 2 diabetes mellitus Read More: http://informahealthcare.com/doi/abs/10.3109/09273948.2014.949779} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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