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izvor podataka: crosbi

Human exposure to ochratoxin A in two cities of Croatia (CROSBI ID 481856)

Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija

Peraica, Maja ; Domijan, Ana-Marija ; Fuchs, Radovan ; Lucić, Ana ; Radić, Božica Human exposure to ochratoxin A in two cities of Croatia // Toxicology Letters. Amsterdam: Elsevier, 2001. str. 42-43-x

Podaci o odgovornosti

Peraica, Maja ; Domijan, Ana-Marija ; Fuchs, Radovan ; Lucić, Ana ; Radić, Božica

engleski

Human exposure to ochratoxin A in two cities of Croatia

Humans are exposed to nephrotoxic mycotoxin ochratoxin A (OTA) mostly by ingestion of contaminated food (cereals, pork meat, wine, beer, coffee, and dry fruits). The aim of our investigation was to find out whether the high consumption of fresh and smoked pork meat and wine during winter period influence the exposure to OTA. Blood samples of healthy volunteers were collected by fifty in Rijeka (at the coast) and in Osijek (inland) in June, September and December 1997 and in January and March 1998. Samples were frozen until analysed by HPLC. The highest frequency of samples with concentration >1 ng OTA/ml as well as the highest mean concentration (0.68 ng/ml of plasma) was found in Osijek in June. In Osijek the lowest frequency of OTA-positive samples (48 %) and the lowest mean OTA concentration (0.28 ng/ml) were found in December. In Rijeka the lowest frequency of positive samples (2 %) and the lowest mean concentration (0.05 ng/ml) were found in September. In Osijek and Rijeka the mean concentration of OTA in January (0.49 and 0.36 ng/ml, respectively) was higher than in December (0.28 and 0.19 ng OTA/ml). In Osijek and Rijeka the daily intake of OTA calculated from the mean concentration (0.54 and 0.18 ng OTA/ml, respectively) was 0.72 and 0.24 ng OTA/kg b.w., respectively, which is much lower than tolerable daily intake proposed by World Health Organization (16.0 ng/kg).

Ochratoxin A; Mycotoxin; Blood donors; Healthy population; Croatia; Daily Intake

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Podaci o prilogu

42-43-x.

2001.

objavljeno

Podaci o matičnoj publikaciji

Toxicology Letters

Amsterdam: Elsevier

Podaci o skupu

Eurotox 2001.

poster

13.09.2001-16.09.2001

Istanbul, Turska

Povezanost rada

Javno zdravstvo i zdravstvena zaštita