engleski

Influence of congenital central nervous system malformations on postoperative complications following placement of cerebrospinal fluid shunts in pediatric and adolescent patients

This retrospective study was designed to evaluate if patients with hydrocephalus associated with CNS anomalies compared to patients with hydrocephalus and absent CNS anomalies, present with significantly higher rate of postoperative complications, including more serious clinical presentation, increased life threat, and higher postoperative or late mortality rate. We performed a retrospective study using medical records of 100 patients of pediatric and adolescent age (0-18 years) between 2004 and 2010 treated with operative CSF shunt placement. In both groups of patients there were 43 postoperative complications, including 12 mechanical obstructions of the CSF drainage systems, 13 disconnections, 11 dislocations of proximal catheter, 6 inflammatory complications (meningitis), and 1 latex allergy. Patients with hydrocephalus associated with CNS anomalies were presented with statistically higher rate of postoperative complications (U=303, 5, z=-3, 27, p=0, 001), higher number of operations, at least one complication more per patient, more complicated clinical course, higher life threat, and higher late mortality rate. Children and adolescents with hydrocephalus associated with anomalies of CNS after installing the CSF drain system requires regularly and carefully follow-up.

congenital anomaly; hydrocephalus; pediatric

nije evidentirano