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Pregled bibliografske jedinice broj: 722787

Ejecting phage DNA against cellular turgor pressure


Marion, Sanjin; Šiber, Antonio
Ejecting phage DNA against cellular turgor pressure // Biophysical journal, 107 (2014), 8; 1924-1929 doi:10.1016/j.bpj.2014.09.002 (međunarodna recenzija, članak, znanstveni)


Naslov
Ejecting phage DNA against cellular turgor pressure

Autori
Marion, Sanjin ; Šiber, Antonio

Izvornik
Biophysical journal (0006-3495) 107 (2014), 8; 1924-1929

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Bacteriophage; DNA ejection; in vivo

Sažetak
We examine in vivo ejection of noncondensed DNA from tailed bacteriophages into bacteria. The ejection is dominantly governed by the physical conditions in the bacteria. The confinement of the DNA in the virus capsid only slightly helps the ejection, becoming completely irrelevant during its last stages. A simple calculation based on the premise of condensed DNA in the cell enables us to estimate the maximal bacterial turgor pressure against which the ejection can still be fully realized. The calculated pressure (∼5 atm) shows that the ejection of DNA into Gram-negative bacteria could proceed spontaneously, i.e., without the need to invoke active mechanisms.

Izvorni jezik
Engleski

Znanstvena područja
Fizika



POVEZANOST RADA


Projekt / tema
035-0352828-2837 - Energetskom kompeticijom uvjetovani oblici i strukture nanometarskih sustava (Antonio Šiber, )

Ustanove
Institut za fiziku, Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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