engleski

A COMPARATIVE ANALYSIS OF EFFECTIVENESS OF TWO GRANULOCYTE COLONY-STIMULATING FACTORS (GCSF), AN ORIGINAL DRUG NEUPOGEN AND A BIOSIMILAR NIVESTIM, IN MOBILISATION OF PERIPHERAL BLOOD STEM CELLS

A retrospective analysis was performed in patients stratified according to GCSF used for mobilisation (Neupogen vs Nivestim) and the hematological malignancy they were treated for (Acute myeloid leukemia, Multiple myeloma, non- Hodgkin`s lymphoma, Hodgkin`s lymphoma) patients who were administered 10 mcg/kg of GCSF were analysed. The following parameters of stem cell mobilisation were surveyed: number of days GCSF was administered, total number of CD34 positive cells per kilogram collected, total number of colony forming units of the granulocyte macrophage order per kilogram collected. A matched pairs analysis was performed on a subset of patients treated for multiple myeloma.

G-CSF ; Peripheral stem cell mobillization ; biosimilars

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