engleski

Investigations on Unsaturated Seconucleoside Analogues

1’, 2’-Unsaturated secoadenosine and secouridine analogues were synthesized by the base promoted regioselective elimination of corresponding ditosylates. Eficient and selective O-detritylation of these acid sensitive compounds was achieved by ZnBr, in dichloromethane.

nucleoside derivatives; protective groups; synthesis

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