A recent bottleneck of Y chromosome diversity coincides with a global change in culture (CROSBI ID 208999)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Karmin, M. ; Saag, L. ; Järve, M. ; Vicente, M. ; Wilson Sayres, M.A. ; Gerst Talas, U. ; Rootsi, S. ; Ilumäe, A.M. ; Reedik, M. ; Mitt, M. ; Pagani, L. ; Puurand, T. ; Faltyskova, Z. ; Clemente, F. ; Cardona, A. ; Metspalu, E. ; Sahakyan, H. ; Yunusbayev, B. ; Hudjashov, G. ; DeGiorgio, M. ; Loogväli, E.L. ; Eichstaedt, C. ; Eelmets, M. ; Chaubey, G. ; Tambets, K. ; Litvinov, S. ; Mormina, M. ; Xue, Y. ; Ayub, Q. ; Zoraqi, G. ; Sand Korneliussen, T. ; Akhatova, F. ; Lachance, J. ; Tishkoff, S. ; Momynaliev, K. ; Ricaut, F.X. ; Kusuma, P. ; Razafindrazaka, H. ; Pierron, D. ; Cox, M.P. ; Nahar Sultana, G.N. ; Willerslev, R. ; Muller, C. ; Westaway, M. ; Lambert, D. ; Škaro, Vedrana ; Kovačević, Lejla ; Turdikulova, S. ; Dalimova, D. ; Khusainova, R. ; Trofimova, N. ; Akhmetova, V. ; Khidyatova, I. ; Lichman, D.V. ; Isakova, J. ; Pocheshkhova, E. ; Sabitov, Z. ; Barashkov, N. ; Nymadawa, P. ; Mihailov, E. ; Tien Seng, J.W. ; Evseeva, I. ; Migliano, A. ; Abdullah, S. ; Andriadze, G. ; Primorac, Dragan ; Atramentova, L. ; Utevska, O. ; Yepiskoposyan, L. ; Marjanović, Damir ; Kushniarevich, A. ; Behar, D.M. ; Gilissen, C. ; Vissers, L. ; Veltman, J. ; Balanovska, E. ; Derenko, M. ; Malyarchuk, B. ; Metspalu, A. ; Fedorova, S. ; Eriksson, A. ; Manica, A. ; Mendez, F. ; Karafet, T. . ; Veeramah, K. ; Bradman, N. ; Hammer, M. ; Osipova, L.P. ; Balanovsky, O. ; Khusnutdinova, E.K. ; Remm, M. ; Thomas, M.G. ; Tyler-Smith, C. ; Underhill, P.A. ; Willerslev, E. ; Nielsen, R. ; Metspalu, Mait ; Villems, R ; Kivisild, T.
engleski
A recent bottleneck of Y chromosome diversity coincides with a global change in culture
It is commonly thought that human genetic diversity in non-African populations was primarily shaped by a recent out-of-Africa dispersal. Here we present a large geographical Y chromosome study using 459 high coverage sequences, including 302 newly reported here. We date the Y chromosomal Most Recent Common Ancestor (MRCA) in Africa at 254 (95% CI 192- 307) kya and differentiation of African and non-African lineages 52-121 kya. The age estimates for major non-African founder haplogroups cluster closely in a narrow time interval at 47-52 kya, consistent with a rapid initial colonization model of Eurasia and Oceania after the out-of-Africa bottleneck. We find that the highest basal Y chromosome diversity outside Africa has been preserved in South and Southeast Asians while extant Y chromosome diversity in Europe and the Near East stems from a small number of mid-Holocene founders. In contrast to demographic reconstructions based on mtDNA, we infer a second strong bottleneck, followed by a fast recovery in Old World populations dating to the last 10 ky. We hypothesize that this bottleneck is caused by cultural changes affecting variance of reproductive success among males.
bottleneck; Y chromosome diversity; global change in culture
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