engleski

The Effect of the Anthropometric Parameters, Age, Vertebral Bone Densitometry and Ash Density on Iliac Crest's Bone Volume and Microstructure

Transiliac bone biopsy is necessary tool in diagnostic procedures, and frequently used method in therapeutic follow-up of the resistant osteoporosis. On the other hand, bone densitometry is the most frequently used technique in estimation of the bone status. The aim was to analyze the extent to which: anthropometry, age, bone densitometry and ash density affect bone changes of the iliac crest, assessed by bone histomorphometry. Iliac crest's bone samples were obtained out of 88 autopsy cases. Prior to bone histomorphometry, two consecutive 5 µm sections were stained and photographed at 40X. Bone samples of the third lumbar vertebra underwent bone densitometry and atomic absorption spectrometry. Results revealed that bone volume (BV/TV) was significantly predicted by age (β = -0, 7), ash density (AD) (β = -0, 23) and BMD (β = 0, 23). Bone surface (BS/TV), trabecular number (Tb.N), trabecular separation (Tb.Sp) and cortical bone volume (CV), were significantly predicted by age, with beta ponder values of: β = -0, 36, β = -0, 75, β = 0, 8 and β = -0, 41, respectively. Trabecular thickness was significantly predicted by age (β = -0, 3) and BMD (β = 0, 44). Cortical thickness was significantly predicted by age (β = 0, 1), body height (β = -2, 4), body weight (β = 3, 8), BMI (β = -2, 5) and BMD (β = 0, 5). Bone mineral density is the strongest and also positive predictor of the iliac crest's trabecular thickness and cortical thickness. This suggests that total amount of the inorganic matter of the scanned vertebral bone surface is strongly related, and therefore, could predict changes that affect the iliac crest's trabecular and cortical thickness.

bone densitometry; ash density; bone

Naziv projekta: Uloga koštanog morfogenetskog proteina - 9 u akutnom i kroničnom oštećenju jetre (broj: 13.06.2.2.63.). Voditelj projekta: doc.dr.sc. Olga Cvijanović, dr. med. Sažetak ovog kongresnog priopćenja objavljen je u Knjizi sažetaka (Zoričić Cvek, Sanja (ur.), (str. 90-90)) i časopisu.