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Pregled bibliografske jedinice broj: 703164

THE RELATIONSHIP BETWEEN ANTI-MüLLERIAN HORMONE (AMH) CONCENTRATION AND OLIGO/AMENORRHOEA IN SUBFERTILE WOMEN WITH POLYCYSTIC OVARIAN MORPHOLOGY


Alebić, Miro Šimun; Stojanović, Nataša
THE RELATIONSHIP BETWEEN ANTI-MüLLERIAN HORMONE (AMH) CONCENTRATION AND OLIGO/AMENORRHOEA IN SUBFERTILE WOMEN WITH POLYCYSTIC OVARIAN MORPHOLOGY // Clin Chem Lab Med 2014 ; 52, Special Suppl, pp S1 – S1760 / Plebani, Mario (ur.).
Berlin: Walter de Gruyter GmbH, 2014. str. S0608-S0608 (poster, međunarodna recenzija, sažetak, znanstveni)


CROSBI ID: 703164 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
THE RELATIONSHIP BETWEEN ANTI-MüLLERIAN HORMONE (AMH) CONCENTRATION AND OLIGO/AMENORRHOEA IN SUBFERTILE WOMEN WITH POLYCYSTIC OVARIAN MORPHOLOGY

Autori
Alebić, Miro Šimun ; Stojanović, Nataša

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Clin Chem Lab Med 2014 ; 52, Special Suppl, pp S1 – S1760 / Plebani, Mario - Berlin : Walter de Gruyter GmbH, 2014, S0608-S0608

Skup
IFCC WorldLab Istanbul 2014

Mjesto i datum
Istanbul. Turska, 22.-26.6.2014

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
AMH; polycystic ovary syndrome; oligo/amenorrhoea

Sažetak
BACKGROUND: Serum anti-Müllerian hormone (AMH) concentration is related to hyperandrogenism (HA) and oligo/amenorrhoea (OA) of polycystic ovary syndrome (PCOS). Objectives of this study were firstly to determine whether AMH is predominantly associated with OA or HA in subfertile women diagnosed as having PCOS according to the Rotterdam criteria (RC) and secondly to determine whether AMH association with the number of follicles measuring 2-9 mm in diameter (AFC) is independent of other clinical and biochemical characteristics that define PCOS. METHODS: A total of 233 subfertile women with polycystic ovarian morphology (PCOM) who met the RC criteria for PCOS were divided into phenotype groups as follows: PCOS A = PCOM+HA+OA, n=90 ; PCOS C = PCOM+HA, n=51 ; PCOS D = PCOM+OA, n=91. PCOM was defined as the presence of >11 AFC in at least one ovary. HA was defined as testosterone (T) concentration >2.8 nmol/L and/or modified Ferriman-Gallwey score (mFG) >7. OA was defined as menstrual cycle length (MCL) >35 days. Kruskal-Walis test with post-hoc analysis for pair wise comparison was used to determine the between-group difference in AMH and other patient characteristics. The relationships between AMH and patient characteristics that define RC were assessed by multiple regression analysis (MRA). P-value <0.05 was considered as statistically significant. RESULTS: Significant difference in AMH was found when two hyperandrogenic PCOS phenotypes differing in MCL (PCOS A vs PCOS C) were compared to each other (P < 0.001). In contrast, the AMH values of the two oligo/anovulatory PCOS phenotypes (PCOS A vs PCOS D) did not differ despite the difference in the signs of HA (P = 0.174). AMH was found to be associated with AFC, T and MCL, but not with mFG. MRA revealed an independent association between AMH and AFC. AMH was included together with MCL, T and mFG in the AFC prediction model explaining 36.9% of the variance of AFC. CONCLUSIONS: OA seems to be the PCOS feature predominantly associated with the AMH concentration in PCOS women having PCOM. The antral follicle accumulation in PCOS could be partially explained by an androgen-independent role of AMH.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
Klinička bolnica "Merkur"

Profili:

Avatar Url Nataša Stojanović (autor)


Citiraj ovu publikaciju:

Alebić, Miro Šimun; Stojanović, Nataša
THE RELATIONSHIP BETWEEN ANTI-MüLLERIAN HORMONE (AMH) CONCENTRATION AND OLIGO/AMENORRHOEA IN SUBFERTILE WOMEN WITH POLYCYSTIC OVARIAN MORPHOLOGY // Clin Chem Lab Med 2014 ; 52, Special Suppl, pp S1 – S1760 / Plebani, Mario (ur.).
Berlin: Walter de Gruyter GmbH, 2014. str. S0608-S0608 (poster, međunarodna recenzija, sažetak, znanstveni)
Alebić, M. & Stojanović, N. (2014) THE RELATIONSHIP BETWEEN ANTI-MüLLERIAN HORMONE (AMH) CONCENTRATION AND OLIGO/AMENORRHOEA IN SUBFERTILE WOMEN WITH POLYCYSTIC OVARIAN MORPHOLOGY. U: Plebani, M. (ur.)Clin Chem Lab Med 2014 ; 52, Special Suppl, pp S1 – S1760.
@article{article, editor = {Plebani, M.}, year = {2014}, pages = {S0608-S0608}, keywords = {AMH, polycystic ovary syndrome, oligo/amenorrhoea}, title = {THE RELATIONSHIP BETWEEN ANTI-M\"{u}LLERIAN HORMONE (AMH) CONCENTRATION AND OLIGO/AMENORRHOEA IN SUBFERTILE WOMEN WITH POLYCYSTIC OVARIAN MORPHOLOGY}, keyword = {AMH, polycystic ovary syndrome, oligo/amenorrhoea}, publisher = {Walter de Gruyter GmbH}, publisherplace = {Istanbul. Turska} }
@article{article, editor = {Plebani, M.}, year = {2014}, pages = {S0608-S0608}, keywords = {AMH, polycystic ovary syndrome, oligo/amenorrhoea}, title = {THE RELATIONSHIP BETWEEN ANTI-M\"{u}LLERIAN HORMONE (AMH) CONCENTRATION AND OLIGO/AMENORRHOEA IN SUBFERTILE WOMEN WITH POLYCYSTIC OVARIAN MORPHOLOGY}, keyword = {AMH, polycystic ovary syndrome, oligo/amenorrhoea}, publisher = {Walter de Gruyter GmbH}, publisherplace = {Istanbul. Turska} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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