Varicella zoster virus DNA does not accumulate in infected human neurons (CROSBI ID 206884)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Baird, NL ; Bowlin, JL ; Yu, X ; Jonjić, Stipan ; Haas, J ; Cohrs, RJ ; Gilden, D.
engleski
Varicella zoster virus DNA does not accumulate in infected human neurons
Varicella zoster virus (VZV) is an exclusively human neurotropic alphaherpesvirus. It is unclear why human neurons infected in vitro with VZV at low multiplicity of infection do not exhibit a cytopathic effect (CPE) even though all VZV genes are transcribed, VZV proteins from all kinetic classes are translated and minimal infectious virus is produced. Here, we show that the lack of VZV-induced CPE correlates with the low abundance of viral DNA
Human neurons; Tissue culture; VZV DNA
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
Podaci o izdanju
Povezanost rada
Temeljne medicinske znanosti