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Pregled bibliografske jedinice broj: 69936

Innflammatory mediators in saliva of patients with rapidly progressive periodontitis during war stress induced incidence increase


Aurer, Andrej; Aurer-Koželj, Jelena; Stavljenić-Rukavina, Ana; Kalenić, Smilja; Ivić-Kardum, Marija; Haban, Vesna
Innflammatory mediators in saliva of patients with rapidly progressive periodontitis during war stress induced incidence increase // Collegium Antropologicum, 23 (1999), 1; 117-124 (međunarodna recenzija, članak, znanstveni)


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Naslov
Innflammatory mediators in saliva of patients with rapidly progressive periodontitis during war stress induced incidence increase

Autori
Aurer, Andrej ; Aurer-Koželj, Jelena ; Stavljenić-Rukavina, Ana ; Kalenić, Smilja ; Ivić-Kardum, Marija ; Haban, Vesna

Izvornik
Collegium Antropologicum (0350-6134) 23 (1999), 1; 117-124

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Sažetak
Rapidly progressive periodontitis (RPP) results from the interaction between the periodontal microflora and the host. Stress is believed to play an important role in determining host responses, and it has been proposed that hyperactivity of host defense mechanism significantly incresed tissue destruction tipical for this disease. During period of four months we have diagnosed 20 patients with acute RPP, all of them active participants in battles of the Croatian liberation war with posttraumatic stress disorder (PTSD) related simptoms. In these patients we analysed biochemical parameters in unstimulated saliva and performed microbiological analysis of periodontal pockets. These findings we compared with those of patients with adult periodontitis (AP), edentulous and healthy persons, none of whom participated in the war. Persons with AP had reduced concentrations of host humoral defense factors in saliva (C-reactive protein, C3 component of complement and alpha-2 macroglobulin), while patients with RPP had increased concentration of interleukin-6 (IL-6). IL-6 is released by host inflammatory cells and is mediator of bone resorption. Actinobacillus actinomycemcomitans and Peptostreptococcus were more frequently isolated in patients with RPP. We interpret these results as indicators of the importance of stress in causation of RPP, with host inflammatory hyperactivity playing an imporatnt role in tissue destruction, especially alveolar bone resorption, possibly caused by increased local levels of IL-6.

Izvorni jezik
Engleski

Znanstvena područja
Dentalna medicina



POVEZANOST RADA


Projekti:
065009

Ustanove:
Stomatološki fakultet, Zagreb


Citiraj ovu publikaciju:

Aurer, Andrej; Aurer-Koželj, Jelena; Stavljenić-Rukavina, Ana; Kalenić, Smilja; Ivić-Kardum, Marija; Haban, Vesna
Innflammatory mediators in saliva of patients with rapidly progressive periodontitis during war stress induced incidence increase // Collegium Antropologicum, 23 (1999), 1; 117-124 (međunarodna recenzija, članak, znanstveni)
Aurer, A., Aurer-Koželj, J., Stavljenić-Rukavina, A., Kalenić, S., Ivić-Kardum, M. & Haban, V. (1999) Innflammatory mediators in saliva of patients with rapidly progressive periodontitis during war stress induced incidence increase. Collegium Antropologicum, 23 (1), 117-124.
@article{article, author = {Aurer, Andrej and Aurer-Ko\v{z}elj, Jelena and Stavljeni\'{c}-Rukavina, Ana and Kaleni\'{c}, Smilja and Ivi\'{c}-Kardum, Marija and Haban, Vesna}, year = {1999}, pages = {117-124}, keywords = {}, journal = {Collegium Antropologicum}, volume = {23}, number = {1}, issn = {0350-6134}, title = {Innflammatory mediators in saliva of patients with rapidly progressive periodontitis during war stress induced incidence increase}, keyword = {} }
@article{article, author = {Aurer, Andrej and Aurer-Ko\v{z}elj, Jelena and Stavljeni\'{c}-Rukavina, Ana and Kaleni\'{c}, Smilja and Ivi\'{c}-Kardum, Marija and Haban, Vesna}, year = {1999}, pages = {117-124}, keywords = {}, journal = {Collegium Antropologicum}, volume = {23}, number = {1}, issn = {0350-6134}, title = {Innflammatory mediators in saliva of patients with rapidly progressive periodontitis during war stress induced incidence increase}, keyword = {} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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