engleski

The impact of valve surgery on mortality in infective endocarditis complicated with embolic stroke: A propensity score analysis

Data were obtained from the International Collaboration on Endocarditis-Prospective Cohort Study of 4794 patients with definite IE who were admitted to 64 centers in 28 countries from June 2000 through December 2006. The treatment group included patients with embolic in whom valve replacement was performed after stroke (225 patients). The control group included medically treated patients (263 patients). Propensity score, which was the estimated probability that a patient would undergo surgery, was calculated for each patient. After propensity score matching, 119 patients were included in each group. In-hospital mortality was significantly higher in the medically treated group than in the surgery group. Overall, in the medically treated group 36 patients (30.3%) died, in the surgery group 16 (15.1%), p=0.005. The odds of hospital death were almost three times higher in the medically treated group, OR=2.806, 95%CI 1.900-4.227. The probability of one-year survival was also significantly higher in surgery group (0.788 vs. 0.567, p<0.001, log-rank test).

Valve surgery ; Infective endocarditis ; Embolic stroke

Abstract from the 12th International Symposium on Modern Concepts in Endocarditis and Cardiovascular Infections, Dubrovnik, Croatia, 19-21 May 2013 ; P75