engleski

The sensitivity of the micronucleus assay for the detection of occupational exposure to vinyl chloride monomer

The micronucleus assay performed in the peripheral lymphocytes of 32 subjects occupationally exposed to vinyl chloride monomer (VCM). In subjects with a longer period of employment micronucleus frequencies decreased in proportion to the length of the interval after the last exposure to VCM. The results confirm that the micronucleus assay can serve as a suitable indicator of the time elapsed after last exposure to elevated concentrations of environmental mutagen.

vinyl chloride; nicronucleus assay; human

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