Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 694717

Centromere identity from the DNA point of view


Plohl, Miroslav; Meštrović, Nevenka; Mravinac, Brankica
Centromere identity from the DNA point of view // Chromosoma (Berlin), 123 (2014), 4; 313-325 doi:10.1007/s00412-014-0462-0 (međunarodna recenzija, pregledni rad, znanstveni)


CROSBI ID: 694717 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Centromere identity from the DNA point of view

Autori
Plohl, Miroslav ; Meštrović, Nevenka ; Mravinac, Brankica

Izvornik
Chromosoma (Berlin) (0009-5915) 123 (2014), 4; 313-325

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
centromere; satellite DNA; transposable elements; transcription

Sažetak
The centromere is a chromosomal locus responsible for the faithful segregation of genetic material during cell division. It has become evident that centromeres can be established literally on any DNA sequence and the possible synergy between DNA sequences and the most prominent centromere identifiers, protein components and epigenetic marks, remains uncertain. However, some evolutionary preferences seem to exist, and long- term established centromeres are frequently formed on long arrays of satellite DNAs and/or transposable elements. Recent progress in understanding functional centromere sequences is based largely on the high-resolution DNA mapping of sequences that interact with the centromere- specific histone H3 variant, the most reliable marker of active centromeres. In addition, sequence assembly and mapping of large repetitive centromeric regions as well as comparative genome analyses offer insight into their complex organization and evolution. The rapidly advancing field of transcription in centromere regions highlights the functional importance of centromeric transcripts. Here, we comprehensively review the current state of knowledge on the composition and functionality of DNA sequences underlying active centromeres and discuss their contribution to the functioning of different centromere types in higher eukaryotes.

Izvorni jezik
Engleski

Znanstvena područja
Biologija



POVEZANOST RADA


Projekti:
098-0982913-2756 - Evolucija, osobitosti i funkcionalne interakcije sekvenci satelitnih DNA (Plohl, Miroslav, MZOS ) ( POIROT)

Ustanove:
Institut "Ruđer Bošković", Zagreb

Citiraj ovu publikaciju

Plohl, Miroslav; Meštrović, Nevenka; Mravinac, Brankica
Centromere identity from the DNA point of view // Chromosoma (Berlin), 123 (2014), 4; 313-325 doi:10.1007/s00412-014-0462-0 (međunarodna recenzija, pregledni rad, znanstveni)
Plohl, M., Meštrović, N. & Mravinac, B. (2014) Centromere identity from the DNA point of view. Chromosoma (Berlin), 123 (4), 313-325 doi:10.1007/s00412-014-0462-0.
@article{article, year = {2014}, pages = {313-325}, DOI = {10.1007/s00412-014-0462-0}, keywords = {centromere, satellite DNA, transposable elements, transcription}, journal = {Chromosoma (Berlin)}, doi = {10.1007/s00412-014-0462-0}, volume = {123}, number = {4}, issn = {0009-5915}, title = {Centromere identity from the DNA point of view}, keyword = {centromere, satellite DNA, transposable elements, transcription} }
@article{article, year = {2014}, pages = {313-325}, DOI = {10.1007/s00412-014-0462-0}, keywords = {centromere, satellite DNA, transposable elements, transcription}, journal = {Chromosoma (Berlin)}, doi = {10.1007/s00412-014-0462-0}, volume = {123}, number = {4}, issn = {0009-5915}, title = {Centromere identity from the DNA point of view}, keyword = {centromere, satellite DNA, transposable elements, transcription} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Citati





    Contrast
    Increase Font
    Decrease Font
    Dyslexic Font