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Pregled bibliografske jedinice broj: 693746

The phylogenetic and geographic structure of Y- chromosome haplogroup R1a

Underhill, Peter A.; ...; Šarić, Tena; Rudan, Pavao; ...; Villems, Richard
The phylogenetic and geographic structure of Y- chromosome haplogroup R1a // European journal of human genetics, 23 (2015), 124-131 doi:10.1038/ejhg.2014.50 (međunarodna recenzija, članak, znanstveni)

The phylogenetic and geographic structure of Y- chromosome haplogroup R1a

Underhill, Peter A. ; ... ; Šarić, Tena ; Rudan, Pavao ; ... ; Villems, Richard

European journal of human genetics (1018-4813) 23 (2015); 124-131

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Y chromosome; R1a; phylogeography

R1a-M420 is one of the most widely spread Y- chromosome haplogroups ; however, its substructure within Europe and Asia has remained poorly characterized. Using a panel of 16 244 male subjects from 126 populations sampled across Eurasia, we identified 2923 R1a- M420 Y-chromosomes and analyzed them to a highly granular phylogeographic resolution. Whole Y-chromosome sequence analysis of eight R1a and five R1b individuals suggests a divergence time of B25 000 (95% CI: 21 300–29 000) years ago and a coalescence time within R1a-M417 of B5800 (95% CI: 4800–6800) years. The spatial frequency distributions of R1a sub- haplogroups conclusively indicate two major groups, one found primarily in Europe and the other confined to Central and South Asia. Beyond the major European versus Asian dichotomy, we describe several younger sub- haplogroups. Based on spatial distributions and diversity patterns within the R1a-M420 clade, particularly rare basal branches detected primarily within Iran and eastern Turkey, we conclude that the initial episodes of haplogroup R1a diversification likely occurred in the vicinity of present-day Iran.

Izvorni jezik

Znanstvena područja
Biologija, Etnologija i antropologija


Projekt / tema
196-1962766-2751 - Populacijska struktura Hrvatske - antropogenetički pristup (Pavao Rudan, )

Hrvatska akademija znanosti i umjetnosti,
Institut za antropologiju

Autor s matičnim brojem:
Jelena Šarac, (308322)
Pavao Rudan, (41641)

Časopis indeksira:

  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus