engleski

The role of anxiety, depression and psychological stress on the clinical status of recurrent aphthous stomatitis and oral lichen planus

Background: In spite of all the efforts recurrent aphthous stomatitis (RAS) and oral lichen planus (OLP) still have unexplained etiology. The role of anxiety, depression and psychological stress in occurrence and intensity of symptoms in RAS and OLP patients has been investigated in this study. Methods: 110 patients with RAS in the acute phase and 112 patients with OLP also in acute phase participated in this study. All patients filled out questionnaires related to the primary disease (RAS/OLP) after which they took the following psychological tests: Beck Depression Inventory (BDI), The State-Trait Anxiety Inventory (STAI) and Ways of Coping Questionnaire (WCQ). Results: According multiple regression analysis, in patients with RAS the highest correlation was found between results of the pain intensity and STAI test (β= 0.66 ; p<0.000). In the patients with OLP the highest correlation was found between level of hyperkeratosis and WCQ test(β= 0.53 ; p<0.000), inflammation and results of BDI test (β= 0.33 ; p<0.002), and results of dynia test and STAI test (β= 0.31 ; p<0.004). Conclusions: The results obtained in this study indicate a high correlation between anxiety, depression, and psychological stress with the symptoms of the RAS and OLP. We may conclude that psychogenic factors play a significant role in symptoms of these diseases and could be associated in initiating pathogenic mechanism of RAS and OLP.

anxiety; depression; oral lichen planus; psychological stress; recurrent aphthous stomatitis

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