engleski

Thyroid cancer in hospital's tyroid disease registry

Aims: By using our registry and analyzing both pathological and clinical data, of our patients, we searched for patterns or distractions in epidemiological and clinical behavior of thyroid cancer during last 20 years. Methods: Thyroid cancer registry was filled with data from post-surgery biopsy findings in the University Hospital, clinical data both preoperative and postoperative and then connected to National Registry of Cancer for follow-up data. Results: Thyroid cancer registry comes with 433 patients in total pool of 3815 thyroid disease patients contained in Hospital’s Thyroid Disease Registry. Papillary cancer is most common with 264 (61%) cases and female to male ratio (F/M) of 3, 3:1. Follicular cancer is next with 72 (16, 6%) cases, F/M of 2:1, medullary carcinoma comes with 35 (8, 1%) cases and F/M ratio of 1, 3:1. Anaplastic cancer with 32 (7.4%) cases and F/M ratio 1, 9:1 formed the smallest group. Survival rates are as follows: 5-year survival for papillary cancer is 97%, follicular cancer 93% and for the medullary carcinoma 78%. In order to gain advanced information considering age distribution we compared average age at diagnosis in two different 2-year periods (1980-81 versus 1997-98). Conclusion: Sex distribution in our registry is as quoted in literature. Follicular cancer is on the lower border of distribution for countries with abnormal iodine uptake what is in correlation with the presence of endemic goiter in Croatia, but with decreasing incidence from 15 in 1980 to 3 in 1997 and none in 1998. Survival rates are as quoted. By comparing two different 2-year periods we found that average age at diagnosis of follicular cancer increased from 45, 5 years (1980- 81) to 61, 3 years (1997-98).

Thyroid cancer in hospital's tyroid disease registry

nije evidentirano