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Pregled bibliografske jedinice broj: 677864

Metabolic and physico-chemical urolithiasis parameters in the first morning urine


Šerić, Vatroslav; Dutour-Sikirić, Maja; Mihaljević, Ivan; Tucak-Zorić, Sandra; Bilić- Čurčić, Ines; Babić-Ivancić, Vesna
Metabolic and physico-chemical urolithiasis parameters in the first morning urine // Collegium antropologicum, 33 (2009), S2; 85-92 (međunarodna recenzija, članak, znanstveni)


Naslov
Metabolic and physico-chemical urolithiasis parameters in the first morning urine

Autori
Šerić, Vatroslav ; Dutour-Sikirić, Maja ; Mihaljević, Ivan ; Tucak-Zorić, Sandra ; Bilić- Čurčić, Ines ; Babić-Ivancić, Vesna

Izvornik
Collegium antropologicum (0350-6134) 33 (2009), S2; 85-92

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Urinary stone formation ; first morning urine ; metabolic urine disorders ; glycosaminoglycans ; risk indices

Sažetak
The 24-hour urine is golden standard for metabolic assessment of stone formers. However, due to the difficulties in collecting almost 1/3 of the samples can not be used for the analysis. Therefore, we analyzed first morning urine and calculated different risk indexes in order to asses possibility of using it in determining urolithiasis risk. Subjects were divided into 4 groups: male patients (n = 31, age 18-64), female patients (n = 31, age 25-63), male controls (n = 16, age 25-64) and female controls (n = 19, age 21-65). First morning urine pH, concentrations of calcium, magnesium, phosphate, sodium, potassium, chloride, citrate, urate, oxalate, creatinine and glycosaminoglycans were determined. Based on them, ionic concentrations and activity products of calcium oxalate and phosphate were calculated by EQUIL 2. In addition, different risk indices were calculated. The results showed that both patients and control groups had metabolic disorders, but the frequencies of occurrence were statistically independent. Significant difference in concentration of urinary constituents between corresponding patient and control groups was observed only for glycosaminoglycans in female subjects. Ca/Cit ratio and Baggio index could differentiate between both corresponding patients and control groups. The results indicate that interplay between stone formation inhibitors and promotors is responsible for urinary stone formation and that the first morning urine could be used in assessing urolithiasis risk and its prevention.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
098-0982904-2951 - Mehanizmi taloženja anorganskih biokompatibilnih i srodnih materijala (Damir Kralj, )
098-0982915-2949 - Površinski aktivne tvari, procesi u otopinama i na međupovršinama (Maja Dutour Sikirić, )
219-2192190-2069 - Fizikalno-kemijski i metabolički čimbenici rizika stvaranja kamenaca (Aleksandar Včev, )
219-2192190-2182 - Osobitosti koštane pregradnje u bolesnika s urolitijazom (Jasminka Milas-Ahić, )
219-2192190-2186 - Prevencija stvaranja i recidiva mokraćnih kamenca (Antun Tucak, )

Ustanove
Institut "Ruđer Bošković", Zagreb,
Klinički bolnički centar Osijek,
Akademija medicinskih znanosti,
Medicinski fakultet, Osijek,
Sveučilište J. J. Strossmayera u Osijeku

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka:


  • Abstracts in Anthropology
  • Agricultural and Environmental Biotechnology Abstracts
  • Anthropological Literature
  • EMBASE (Excerpta Medica)
  • IBSS - The International Bibliography of the Social Sciences
  • MEDLINE