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Pregled bibliografske jedinice broj: 677788

S-adenosyl-L-methionine production by an ergosterol-deficient mutant of Scheffersomyces stipitis


Križanović, Stela; Mrvčić, Jasna; Stanić, Marina; Cepanec, Maja; Stanzer, Damir
S-adenosyl-L-methionine production by an ergosterol-deficient mutant of Scheffersomyces stipitis // Croatian Journal of Food Technology, Biotechnology and Nutrition, 8 (2013), 1-2; 21-28 (podatak o recenziji nije dostupan, članak, znanstveni)


Naslov
S-adenosyl-L-methionine production by an ergosterol-deficient mutant of Scheffersomyces stipitis

Autori
Križanović, Stela ; Mrvčić, Jasna ; Stanić, Marina ; Cepanec, Maja ; Stanzer, Damir

Izvornik
Croatian Journal of Food Technology, Biotechnology and Nutrition (1847-3423) 8 (2013), 1-2; 21-28

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
S-adenosyl-L-methionine (SAM; SAMe; AdoMet); Scheffersomyces stipitis (former Pichia stipitis); nystatin

Sažetak
S-adenosyl-L-methionine (SAM, SAMe ; AdoMet) is an important methyl donor in many reactions, and recently has attracted much attention due to its expanding application in pharmacy. Efficient ways of its production have been widely researched. In this study it was demonstrated that erg6 mutant of yeast Scheffersomyces stipitis (former Pichia stipitis), obtained by UV mutagenesis and selected by resistance to nystatin, could be used for production of SAM. The mutant strain showed higher ability to accumulate SAM than its parental strain. The experiments demonstrated different dependence of erg6 mutant strain on several cultivation conditions in comparison to parental strain, its higher sensibility to oxidative stress, as well as strong dependence of SAM accumulation on the cell growth phase and supplementation of growth media with methionine..

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija, Prehrambena tehnologija



POVEZANOST RADA


Projekt / tema
058-0580477-0374 - Proizvodnja biološki aktivnih tvari pomoću selekcioniranih kvasaca (Damir Stanzer, )
058-0583444-3483 - Mineralima obogaćene funkcionalne starter kulture u prehrambenoj industriji (Vesna Stehlik-Tomas, )

Ustanove
Prehrambeno-biotehnološki fakultet, Zagreb

Uključenost u ostale bibliografske baze podataka:


  • FSTA: Food Science and Technology Abstracts