Nalazite se na CroRIS probnoj okolini. Ovdje evidentirani podaci neće biti pohranjeni u Informacijskom sustavu znanosti RH. Ako je ovo greška, CroRIS produkcijskoj okolini moguće je pristupi putem poveznice www.croris.hr
izvor podataka: crosbi

Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production (CROSBI ID 202143)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Grausenburger, Reinhard ; Bilić, Ivan ; Boucheron, Nicole ; Zupkovitz, Gordin ; El-Housseiny, Lamia ; Tschismarov, Roland ; Zhang Yu ; Rembold, Martina ; Gaisberger, Martin ; Hartl, Arnulf et al. Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production // Journal of immunology, 185 (2010), 6; 3489-3497. doi: 10.4049/jimmunol.0903610

Podaci o odgovornosti

Grausenburger, Reinhard ; Bilić, Ivan ; Boucheron, Nicole ; Zupkovitz, Gordin ; El-Housseiny, Lamia ; Tschismarov, Roland ; Zhang Yu ; Rembold, Martina ; Gaisberger, Martin ; Hartl, Arnulf ; Epstein, Michelle ; Matthias, Patric ; Seiser, Christian ; Ellmeier, Wilfried

engleski

Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production

Chromatin modifications, such as reversible histone acetylation, play a key role in the regulation of T cell development and function. However, the role of individual histone deacetylases (HDACs) in T cells is less well understood. In this article, we show by conditional gene targeting that T cell-specific loss of HDAC1 led to an increased inflammatory response in an in vivo allergic airway inflammation model.

T lymphocytes; development

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

Podaci o izdanju

185 (6)

2010.

3489-3497

objavljeno

0022-1767

10.4049/jimmunol.0903610

Povezanost rada

Temeljne medicinske znanosti, Kliničke medicinske znanosti, Biologija

Poveznice
Indeksiranost