Biomimetic Radical Chemistry by g-Irradiation of Micelles and Vesicle Containing Fatty Acid Residues (CROSBI ID 202079)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Chatgilialoglu, Chryssostomos ; Ferreri, Carla ; N. Lykakis, Ioannis ; Mihaljević, Branka
engleski
Biomimetic Radical Chemistry by g-Irradiation of Micelles and Vesicle Containing Fatty Acid Residues
Different types of lipid aggregations, such as micelles and liposomes, can be used as biomimetic models. The uses of gamma irradiation as a valid methodology for simulating the biological generation of thiyl radicals in these models are summarized and in particular, thiyl radical-catalyzed cis–trans isomerization of unsaturated lipids is underlined. The efficiency of antioxidants against lipid isomerization assayed by biomimetic models and the importance of trans lipids as novel biomarkers of radical stress are also described.
antioxidant; fatty acid; free radical; liposome; gamma radiolysis
Special Issue: Radiation Chemistry.
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